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Diabetes

Oral glucose tolerance test and continuous glucose monitoring for gestational diabetes diagnosis: a survey study of women and health care professionals.

Feb 06, 2023

The oral glucose tolerance test (OGTT), used for gestational diabetes mellitus (GDM) diagnosis for over 65 years, has poor acceptability and tolerability. Continuous glucose monitoring is being consi...

fermentation assay on the bifidogenic effect of steviol glycosides of plant for the development of dietetic novel products.

Jan 30, 2023

The relationship between excessive sugar consumption and many diseases such as dental caries, obesity, diabetes and coronary heart has been increasing in recent years. In this study, utilization of na...

Long-term lithium therapy and risk of chronic kidney disease, hyperparathyroidism and hypercalcemia: a cohort study.

Jan 30, 2023

Lithium is well recognized as the first-line maintenance treatment for bipolar disorder (BD). However, besides therapeutic benefits attributed to lithium therapy, the associated side effects including...

Physician-led medication reviews in polypharmacy patients treated with at least 12 medications in a type 2 diabetes outpatient clinic: a randomised trial.

Jan 23, 2023

Medication reviews can be used to promote appropriate pharmacotherapy and negate the harmful consequences of polypharmacy. This study aimed to evaluate the effect of physician-led medication reviews a...

[The association between diabetes complications and symptoms of depression and anxiety].

Jan 23, 2023

The bidirectional relationship between diabetes and depression results in severe disease burden. Co-occurring depression is associated with a higher rate of diabetes complications. These complications...

Nailfold capillaroscopy and deep learning in diabetes.

Jan 16, 2023

To determine whether nailfold capillary images, acquired using video capillaroscopy, can provide diagnostic information about diabetes and its complications.Nailfold video capillaroscopy was performed...

Applications of continuous glucose monitoring across settings and populations: report from the 23 Hong Kong Diabetes and Cardiovascular Risk Factors - East Meets West Symposium.

Jan 09, 2023

Continuous glucose monitoring (CGM) is now an integral part of glycaemic management in people with type 1 diabetes and in those with insulin-treated type 2 diabetes. Immediate access to information on...

A Pilot Study of Mealtime Insulin Administration and Parental Stress in Youth with New-Onset Type 1 Diabetes.

Jan 09, 2023

To compare the stress level in parents of children with new-onset type 1 diabetes receiving a fixed insulin dose for a fixed range of carbohydrates (CHOs) to parents of children receiving a precise in...

High-density lipoprotein subclasses and cardiovascular disease and mortality in type 2 diabetes: analysis from the Hong Kong Diabetes Biobank.

Jan 02, 2023

High-density lipoproteins (HDL) comprise particles of different size, density and composition and their vasoprotective functions may differ. Diabetes modifies the composition and function of HDL. We a...

Implications of genetic variations, differential gene expression, and allele-specific expression on metformin response in drug-naïve type 2 diabetes.

Dec 19, 2022

Metformin is widely used to treat type 2 diabetes mellitus (T2DM) individuals. Clinically, inter-individual variability of metformin response is of significant concern and is under interrogation. In t...

Engineered probiotics Clostridium butyricum-pMTL007-GLP-1 improves blood pressure via producing GLP-1 and modulating gut microbiota in spontaneous hypertension rat models.

Dec 19, 2022

Hypertension is a significant risk factor of cardiovascular diseases (CVDs) with high prevalence worldwide, the current treatment has multiple adverse effects and requires continuous administration. T...

Characterization of advanced glycation end products and aggregates of irisin: Multispectroscopic and microscopic approaches.

Dec 12, 2022

Glycation of proteins leading to the formation of advanced glycation end products (AGEs) has been demonstrated to contribute to the pathogenesis of several diseases. Irisin is a clinically significant...

PHEVIR: an artificial intelligence algorithm that predicts the molecular role of pathogens in complex human diseases.

Dec 05, 2022

Infectious diseases are known to cause a wide variety of post-infection complications. However, it's been challenging to identify which diseases are most associated with a given pathogen infection. Us...

Clinical outcomes with delayed mechanical thrombectomy: Descriptive analysis and development of a screening tool.

Dec 05, 2022

Limited data guides selection of patients with large vessel occlusion ischaemic stroke who may benefit from referral to a distant tertiary centre for mechanical thrombectomy (MT).We undertook a retros...

#VisualAbstract: Pemafibrate does not reduce cardiovascular risk in patients with type 2 diabetes and elevated triglycerides

Nov 11, 2022

Click here to read this study in NEJM. ...

#VisualAbstract: Continuous glucose monitoring in type 1 diabetes results in improved blood glucose levels

Oct 31, 2022

1. In patients with type 1 diabetes, using intermittently scanned continuous glucose monitoring resulted in significantly lower glycated hemoglobin levels than levels monitored by fingerstick test...

#VisualAbstract: Dulaglutide improves glycemic control for youth with type 2 diabetes

Aug 19, 2022

1. Dulaglutide significantly reduced baseline glycated hemoglobin levels as compared to a placebo control in youth with type 2 diabetes (T2DM). 2. Dulaglutide use was not significantly associat...

Predictability of Metabolic Syndrome Diagnosed by Body Mass Index for Cardiovascular Risk in Older Patients Treated with Levothyroxine.

Jun 22, 2022

We investigated the prevalence and metabolic features of two definitions of multiple sclerosis (MS) between older patients with chronic thyroiditis treated with levothyroxine (LT4) and controls. We al...

Clinically Elevated Parent Depressive Symptoms and Stress at Child Type 1 Diabetes Diagnosis: Associations with Parent Diabetes Self-Efficacy at 18-Months Post-Diagnosis.

May 23, 2022

Eighteen percent of new diagnoses of type 1 diabetes (T1D) occur in children ages 9 and younger, and the burden of diabetes management in young children predominantly falls on parents. Despite the sig...

Continuous metabolic syndrome severity score and the risk of CVD and all-cause mortality.

May 23, 2022

The dualistic diagnostic criteria for metabolic syndrome overlooked the severity of metabolic syndrome, and the relationships between the severity of metabolic syndrome and adverse health conditions a...