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Diabetes

Mitigation of the Adverse Consequences of Nutrient Excess on the Kidney: A Unified Hypothesis to Explain the Renoprotective Effects of Sodium-Glucose Cotransporter 2 Inhibitors.

Mar 04, 2020

The 2 most common causes of chronic kidney disease worldwide (type 2 diabetes and obesity) are states of nutrient excess, suggesting that fuel overabundance leads to deleterious effects on the structu...

Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes.

Mar 02, 2020

Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipocytes. NNMT expression in adipose tissue is increased in obesity and diabetes. Knockdown of NNMT prevents mic...

Perivascular adipose tissue in age-related vascular disease.

Mar 02, 2020

Perivascular adipose tissue (PVAT), a crucial regulator of vascular homeostasis, is actively involved in vascular dysfunction during aging. PVAT releases various adipocytokines, chemokines and growth ...

Korean red ginseng attenuates hyperglycemia-induced renal inflammation and fibrosis via accelerated autophagy and protects against diabetic kidney disease.

Mar 02, 2020

Panax ginseng C.A. Mey. (Korean ginseng) has been widely used in traditional medicine to treat diabetes mellitus for thousands of years. It also plays a key role in health maintenance owing to its ant...

Long-term tooth retention in periodontitis patients in four German university centres.

Mar 02, 2020

In this retrospective study, we compared tooth loss between patients receiving periodontal therapy (PT) in four German university centres, stratified according to periodontal treatment phase.Overall, ...

Investigation of SIRT1 gene variants in HIV-associated lipodystrophy and metabolic syndrome.

Feb 28, 2020

HIV-infected individuals on chronic use of highly active antiretroviral therapy (HAART) are more likely to develop adipose tissue and metabolic disorders, such as lipodystrophy (LD) and metabolic synd...

Photoreceptor Degeneration Accompanies Vascular Changes in a Zebrafish Model of Diabetic Retinopathy.

Feb 28, 2020

Diabetic retinopathy (DR) is a leading cause of vision impairment and blindness worldwide in the working-age population, and the incidence is rising. Until now it has been difficult to define initiati...

Does Self-Efficacy Mediate the Link Between Impulse Control and Diabetes Adherence?

Feb 28, 2020

The goal of this study was to test the hypothesis that diabetes self-efficacy mediates the relationship between impulse control and type 1 diabetes (T1D) management from ages 8 to 18 years, using mult...

Treatment of periodontitis reduces systemic inflammation in type 2 diabetes.

Feb 28, 2020

To assess the impact of periodontal treatment on systemic inflammation in type 2 diabetes.Adults with type 2 diabetes (n=83) and without diabetes (controls, n=75) were recruited, and participants with...