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Diabetes

Dulaglutide reduces binge episodes in type 2 diabetic patients with binge eating disorder: A pilot study.

Apr 15, 2020

Binge eating disorder (BED) is the most common eating disorder in the United States and Europe and is associated with obesity and type 2 diabetes (T2D). Presence and severity of BED have been associat...

Effect of green tea extract on lipid profile in patients with type 2 diabetes mellitus: A systematic review and meta-analysis.

Apr 15, 2020

Previous studies have indicated controversial results regarding the efficacy of green tea extract (GTE) in improving the lipid profile of type 2 diabetes mellitus (T2DM) patients. We aimed to conduct ...

Statin Lipophilicity and the Risk of Incident Heart Failure.

Apr 15, 2020

To compare the risk of incident heart failure (HF) between initiators of hydrophilic and lipophilic statins.Using claims data for commercial health insurance program enrollees in the USA (2005-2014), ...

A Single Motivational Lecture Can Promote Modest Weight Loss: A Randomized Controlled Trial.

Apr 15, 2020

Obesity is a public health problem worldwide. To widely disseminate weight-loss interventions across the target population, a cost-effective approach is needed.We aimed to test whether a single motiva...

Antidiabetic Therapy and Rate of Severe Hypoglycaemia in Patients with Type 2 Diabetes and Chronic Kidney Disease of Different Stages - A Follow-up Analysis of Health Insurance Data from Germany.

Apr 15, 2020

The presence of chronic kidney disease (CKD) influences the type of antiglycaemic therapy and the risk for hypoglycaemia.In 2006, 2011 and 2016 health insurance data of people with diabetes type 2 wer...

Comparison and analyses of therapeutic effects between metabolic management center (MMC) and conventional management modes.

Apr 06, 2020

The past 3 decades witnessed the rapid growth of diabetes in China. To better serve large numbers of patients, the Chinese Medical Doctor Association launched metabolic management center (MMC) progra...

Clinical evidence regarding factors linking metabolic abnormal obesity to pancreatic beta cell dysfunction.

Apr 06, 2020

In the past few decades, the prevalence of obesity has increased not only in Western countries but also in Asia. Obesity is frequently accompanied by unhealthy adipocyte expansion; this results in a c...

Interactions between ocular and systemic disease using national register-based data in the Danish Excellence Centre in Ophthalmic Epidemiology (DECODE-EYE): study perspective.

Apr 06, 2020

The Danish Excellence Centre in Ophthalmic Epidemiology (DECODE-EYE) is a national research collaboration formed in order to study the real-life interaction between ocular and systemic disease based o...

Controversial aspects of testosterone in the regulation of sexual function in late onset hypogonadism.

Apr 06, 2020

Testosterone (T) plays a pivotal role in coordinating a series of psychological, cognitive and physical events that might (or might not) culminate in male sexual activity. In fact, T deficiency is ass...

Metformin revert insulin-induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells.

Apr 06, 2020

Several studies have suggested that drug resistance in colon cancer patients with diabetes may be associated with long-term insulin administration, which in turn decreases the survival rate. Metformin...

Aspirin Versus Clopidogrel Monotherapy for the Secondary Prevention of Recurrent Cerebrovascular Attack Following Previous Ischemic Stroke in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Mar 30, 2020

Type 2 diabetes mellitus (T2DM) and stroke are two different diseases, but have many aspects in common. Aspirin is recommended as an initial treatment for the secondary prevention of recurrent ischemi...

Organ-protective Effect of Angiotensin-converting Enzyme 2 and its Effect on the Prognosis of COVID-19.

Mar 30, 2020

This article reviews the correlation between ACE2 and severe risk factors for COVID-19 and the possible mechanisms. Angiotensin-converting enzyme 2 (ACE2) is a crucial component of the renin-angiotens...

Effect of Abelmoschus esculentus (okra) on metabolic syndrome: A review.

Mar 30, 2020

Metabolic syndrome is a disorder characterized by dyslipidemia, insulin resistance, abdominal fat, high blood pressure, hypertriglyceridemia, and diminished high density lipoprotein cholesterol. Okra ...

Inflammation and central adiposity as mediators of depression and uncontrolled diabetes in the study on global AGEing and adult health (SAGE).

Mar 30, 2020

Diabetes and depression are commonly present in the same individuals, suggesting the possibility of underlying shared physiological processes. Inflammation, as assessed with the biomarker C-reactive p...

Improving Pediatric Endocrinology Trainees' Knowledge about Insulin Pumps and Continuous Glucose Monitors with Online Spaced Education: Technology Knowledge Optimization in T1D (TeKnO T1D).

Mar 30, 2020

We explored the impact of TeKnO T1D, an online, case-based, spaced education curriculum about insulin pump and continuous glucose monitor (CGM) use in pediatric type 1 diabetes management.Pediatric en...

Rupatadine, a dual antagonist of histamine and platelet-activating factor (PAF), attenuates experimentally induced diabetic nephropathy in rats.

Mar 23, 2020

The role of histamine and platelet activating factor (PAF) as involved mediators in the pathophysiology of diabetic complications, in particular diabetic nephropathy (DN), has become a new focus of co...

Renal functional impairment in the elderly, the importance of fasting plasma glucose: the Northern Shanghai Study.

Mar 23, 2020

Chronic kidney disease is a global health problem that is closely related to the aging population. Although plasma glucose levels have been shown to be related to renal dysfunction, risk factors for r...

Glucose Lowering Treatment Modalities of Type 2 Diabetes Mellitus.

Mar 23, 2020

This chapter gives an overview of present knowledge and clinical aspects of antidiabetic drugs according to the recently available research evidence and clinical expertise.Many agents are acting on ei...

Features of cotton wool spots in diabetic retinopathy: a spectral-domain optical coherence tomography angiography study.

Mar 23, 2020

To describe the features of cotton wool spots (CWSs) in diabetic retinopathy (DR) by using spectral-domain optical coherence tomography (SD-OCT) and optical coherence tomography angiography (OCT angio...

Serum irisin levels as a potential marker for diagnosis of gestational diabetes mellitus.

Mar 20, 2020

The aim of this study was to compare serum irisin, trace elements (Zn, Cu, Mg) levels between the group of pregnant women with gestational diabetes mellitus (GDM) and healthy pregnant group.Sixty preg...