Diabetes
May 05, 2020
Methyltransferase-like protein 3 (METTL3) regulates multiple cell functions and diseases by modulating N-methyladenosine (mA) modifications. However, it is still unclear whether METTL3 involves in the...
May 05, 2020
Aimed to find the cut-off point of handgrip strength and it's association with MetS.The relative handgrip strength was negatively associated with the prevalence of MetS. Of note, the odds ratios (ORs)...
May 05, 2020
De novo lipogenesis is tightly regulated by insulin and nutritional signals to maintain metabolic homeostasis. Excessive lipogenesis induces lipotoxicity, leading to nonalcoholic fatty liver disease (...
May 05, 2020
Chronic Kidney Disease of uncertain etiology (CKDu) is an endemic, disease that mostly affects young agricultural workers in the rural dry zone of Sri Lanka. This study was designed to identify specif...
May 05, 2020
Individualized treatment rules (ITRs) tailor medical treatments according to patient-specific characteristics in order to optimize patient outcomes. Data from randomized controlled trials (RCTs) are u...
May 05, 2020
Nonnutritive sweeteners (NNSs)—also known as non-caloric artificial sweeteners or high-intensity sweeteners—are common in food, beverages, condiments, and even gum. NNSs have been proposed for use...
May 01, 2020
To compare the prevalence of diabetic retinopathy (DR) and diabetic macular edema (DME), as well as their risk factors in patients with early onset diabetes (EOD, ≤40 years) and late onset diabetes ...
May 01, 2020
To investigate the association between baseline plasma zinc-α2-glycoprotein and non-albuminuric chronic kidney disease progression in type 2 diabetes.Adults with normoalbuminuria at entry (n=341; age...
May 01, 2020
To compare diagnosis characteristics, diabetes management and comorbidities in a population diagnosed with type 1 diabetes in childhood with those in a similar population diagnosed in adulthood to ide...
May 01, 2020
The clinical features of COVID-19 range from a mild illness to patients with a very severe illness with acute hypoxemic respiratory failure requiring ventilation and Intensive Care Unit admission. Ris...
May 01, 2020
Acute oxygen inhalation and slow deep breathing improve measures of autonomic function transiently in individuals with short-duration type 1 diabetes. Our aims were to examine these interventions and ...
Apr 28, 2020
Diabetic nephropathy (DN), a common complication of diabetes mellitus, is the main cause of end-stage nephropathy, and thus developing novel strategies for reversing DN remains urgent. Astragaloside I...
Apr 28, 2020
Acromegaly is a disease characterized by overproduction of growth hormone (GH). As a consequence of excessive GH secretion, circulating insulin-like growth factor-I (IGF-I) is elevated in active (untr...
Apr 28, 2020
To evaluate the oral health status, oral health related habits and halitosis of children with and without type 1 diabetes.In this study oral health status of children with and without type 1 diabetes ...
Apr 28, 2020
COVID-19 is a rapidly spreading outbreak globally. Emerging evidence demonstrates that older individuals and people with underlying metabolic conditions of diabetes mellitus, hypertension, and hyperli...
Apr 28, 2020
Thiazolidinediones (TZDs) improve glycaemic control, and ameliorate liver steatosis, inflammation, and fibrosis in patients with fatty liver disease. We aimed to study the impact of TZD and glycaemic ...
Apr 20, 2020
To evaluate the variation in parameters of hepatic function and in the scores Fatty Liver Index (FLI; predictor of hepatic steatosis) and BARD (BMI, AST/ALT ratio and DM, predictor of hepatic fibrosis...
Apr 20, 2020
Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, was shown in the DAPA-HF study to reduce the risk of worsening heart failure or death in symptomatic patients with left ejection fraction < 4...
Apr 20, 2020
Hyperlipidaemia is a common phenomenon in diabetes mellitus. Fenofibrate (FF) is a good candidate for the treatment of lipid abnormalities in patients with type 2 diabetes. But the bioavailability as ...
Apr 20, 2020
Fast-acting insulin aspart (faster aspart) is a novel formulation of insulin aspart (IAsp) ensuring ultra-fast absorption and effect.To compare the pharmacokinetics between faster aspart and IAsp, bas...