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Diabetes

Clinical and neuroimaging correlates of progression of mild parkinsonian signs in community-dwelling older adults.

Jun 08, 2020

Mild parkinsonian signs (MPS) are associated with morbidity. Identification of MPS progression markers may be vital for preventive management, yet has not been pursued. This study aimed to ascertain c...

Racial Disparity in Postpartum Readmission due to Hypertension among Women with Pregnancy-Associated Hypertension.

Jun 04, 2020

 Postpartum hypertension is a leading cause of readmission in the postpartum period. We aimed to examine the prevalence of racial/ethnic differences in postpartum readmission due to hypertension in ...

Whole-body Electromyostimulation plus Caloric Restriction in Metabolic Syndrome.

Jun 04, 2020

We investigated early effects of Whole-Body Electromyostimulation added to hypocaloric diet on metabolic syndrome features in sedentary middle-aged individuals. We randomly assigned 25 patients to Who...

Stem cell mobilization with plerixafor and healing of diabetic ischemic wounds: A phase IIa, randomized, double-blind, placebo-controlled trial.

Jun 04, 2020

Bone marrow-derived cells contribute to tissue repair, but traffic of hematopoietic stem/progenitor cells (HSPCs) is impaired in diabetes. We therefore tested whether HSPC mobilization with the CXCR4 ...

Flavonoids modulate tight junction barrier functions in hyperglycemic human intestinal Caco-2 cells.

Jun 01, 2020

Diabetes mellitus is a chronic disease requiring lifelong medical attention. With hundreds of millions suffering worldwide and a rapidly rising incidence, diabetes mellitus poses a great burden on hea...

Acute Liver Injury in COVID-19: Prevalence and Association with Clinical Outcomes in a Large US Cohort.

Jun 01, 2020

Coronavirus disease 2019 (COVID-19) has been associated with acute liver injury manifested by increased liver enzymes in reports worldwide. Prevalence of liver injury and associated clinical character...

Display of quintuple glucagon-like peptide 1 (28-36) nonapeptide on Bacillus subtilis spore for oral administration in the treatment of type 2 diabetes.

Jun 01, 2020

To develop an oral delivery system of glucagon-like peptide 1 (GLP-1)(28-36) for treating Type-2 Diabetes, B.S-GLP-1(28-36), a recombinant Bacillus subtilis spores transformed with a plasmid vector en...

Acute Improvement in Intraoperative EMG During Common Fibular Nerve Decompression in Patients with Symptomatic Diabetic Sensorimotor Peripheral Neuropathy: EMG and Clinical Attribute Interrelations.

May 28, 2020

 Electromyographic (EMG) recordings of the fibularis longus and tibialis anterior muscles were performed intraoperatively during nerve decompression (ND) of the common fibular nerve (CFN) in patient...

Validation of Postpartum Hemorrhage Admission Risk Factor Stratification in a Large Obstetrics Population.

May 28, 2020

 This study aimed to evaluate the performance of the California Maternal Quality Care Collaborative (CMQCC) admission risk criteria for stratifying postpartum hemorrhage risk in a large obstetrics p...

Management of pyogenic liver abscess: a South Australian experience.

May 28, 2020

There have been declining mortality rates associated with pyogenic liver abscess (PLA) in recent decades due to improvements in percutaneous drainage techniques, access to imaging and improvements in ...

Inadequate achievement of ABC goals (HbA1c, blood pressure, LDL-C) among patients with type 2 diabetes in an Iranian population, 2012-2017.

May 19, 2020

This study was designed to evaluate the meeting of ABC goals in patients with type 2 diabetes. The ABC goals were defined as meeting the HbA1c ...

Gender differences in the risk factors for high and very high blood glucose levels: A study of Kerala.

May 19, 2020

Worldwide, lifestyle is a significant risk factor for diabetes. Lifestyle changes can lead to differences in the extent of risk of diabetes among women and men. Kerala, a state with one of the best he...

Polysaccharides from Opuntia milpa alta alleviate alloxan-induced INS-1 cells apoptosis via reducing oxidative stress and upregulating Nrf2 expression.

May 19, 2020

The incidence and progression of type 2 diabetes are closely related to pancreatic β-cell damage. Oxidative stress may be one of the key factors contributing to β-cell apoptosis. Opuntia milpa alta ...

Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy.

May 19, 2020

Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual disability and blindness in diabetic patients. Chronic hyperglycemia leads to increased oxidative st...

Demographic Characteristics Among Patients With Chronic Exertional Compartment Syndrome of the Lower Leg.

May 19, 2020

Clinical Scenario: Chronic exertional compartment syndrome (CECS) is a condition related with ischemia of the body's tissue due to increases in intracompartmental pressures, which involves, among othe...

Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study.

May 12, 2020

Regulatory agencies warn about the risk of acute kidney injury (AKI) after the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to quantify the 90-day risk of AKI in ...

Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase.

May 12, 2020

The lemon essential oil (LEO), extracted from the fruit of lemon, has been used to treat multiple pathological diseases, such as diabetes, inflammation, cardiovascular diseases, depression and hepatob...

Risk Factors for Lower Extremity Amputation Following Attempted Free Flap Limb Salvage.

May 12, 2020

 Traumatic limb salvage with free flap reconstruction versus primary amputation for lower extremity (LE) injuries remains an oft debated topic. Limb salvage has well-studied benefits and advances in...

Changes in Blood Glucose Level After Steroid Injection for Musculoskeletal Pain in Patients With Diabetes.

May 12, 2020

To investigate changes in blood glucose level after steroid injection in patients with type 2 diabetes mellitus (DM) and factors affecting those changes.We retrospectively studied 51 patients with typ...

Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea.

May 12, 2020

We aimed to evaluate site-specific cancer risk in diabetic patients and to investigate causal and temporal relationships by analyzing organ-specific cancer risk according to the duration of diabetes.U...