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Diabetes

LncRNA H19 inhibits high glucose-induced inflammatory responses of human retinal epithelial cells by targeting miR-19b to increase SIRT1 expression.

Oct 08, 2020

Diabetic retinopathy (DR) is a common complication of diabetes mellitus. Inflammatory responses play crucial roles in the progress of DR. Long noncoding RNA (lncRNAs) and microRNAs (miRNAs) are key si...

Effects of "metabolic memory" on erectile function in diabetic men: a retrospective case-control study.

Oct 08, 2020

This study was performed to explore the effects of metabolic memory on diabetic erectile dysfunction (ED), especially the severity and response to treatment.Through medical records and follow-up by te...

A Closer Look at the Association of Alcohol Intake With Hypertension in Type 2 Diabetes

Oct 05, 2020

Hypertension is a major global public health concern and continues to be the leading cause of premature cardiovascular morbidity and death. In the 2017 American College of Cardiology/American Heart As...

Association of aldehyde exposure with cardiovascular disease.

Oct 05, 2020

The effect of aldehyde exposure on the cardiovascular system remains unclear. The objective of this study was to determine whether aldehyde exposure is associated with the prevalence of cardiovascular...

MiR-193b inhibits autophagy and apoptosis by targeting IGFBP5 in high glucose-induced trophoblasts.

Oct 05, 2020

Inhibiting apoptosis of trophoblasts in women with gestational diabetes mellitus (GDM) is expected to guarantee adequate nutrition for the fetus and avoid abortion. MiR-193b is one of the most downreg...

Diabetes, prediabetes, and suicide deaths in a Japanese working population.

Oct 05, 2020

To examine the association of diabetes and prediabetes with suicide deaths in a Japanese working population.A nested case-control study was conducted using data from the Japan Epidemiology Collaborati...

Obstructive sleep apnea in patients with diabetes less than 40 years of age.

Oct 01, 2020

Obstructive sleep apnea (OSA) is known to be associated with diabetes mellitus (DM). Age is factor associated with different clinical features of OSA. There is limited data on clinical differences of ...

Metabolite signature of albuminuria involves amino acid pathways in 8,661 Finnish men without diabetes.

Oct 01, 2020

To investigate metabolite signature of albuminuria in individuals without diabetes or chronic kidney disease to identify possible mechanisms resulting in increased albuminuria and elevated risk of T2D...

Maternity services in the UK during the COVID-19 pandemic: a national survey of modifications to standard care.

Oct 01, 2020

To explore the modifications to maternity services across the UK, in response to the COVID-19 pandemic, in the context of the pandemic guidance issued by the Royal College of Obstetricians and Gynaeco...

Trend in the clinical profile of type 2 diabetes in India - Study from a diabetes care centre in South India.

Sep 28, 2020

Study the changing clinical and therapeutic profiles of type 2 diabetes (T2D) patients during a 10-year period in a diabetes care centre in Southern India.Retrospective, cross-sectional data of newly ...

Inhibition of fatty acid binding protein 4 attenuates gestational diabetes mellitus.

Sep 28, 2020

Accumulatig evidence demonstrated that inflammation is associated with the development of gestational diabetes mellitus (GDM). Fatty acid-binding protein 4 (FABP4) was reported to be involved in immun...

NT-proBNP as predictor factor of cardiotoxicity during trastuzumab treatment in breast cancer patients.

Sep 28, 2020

Trastuzumab is a drug used in HER2-positive breast cancer that increases patient survival. Due to cardiotoxicity is the most important side effect of trastuzumab treatment, cardiac monitoring should b...

Prevalence and factors associated with non-alcoholic fatty liver disease in Indian women with a history of gestational diabetes mellitus.

Sep 24, 2020

This study evaluates the prevalence and factors associated with NAFLD in Indian women with prior GDM diagnosed using IADPSG criteria.This cross-sectional study (2018-2019) enrolled women with and with...

Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: an IRMA2 sub-study.

Sep 24, 2020

Angiotensin receptor blockers (ARBs) reduce vascular complications in diabetes independently of blood pressure. Experimental studies suggested that ARBs may restore the detoxifying enzyme glyoxalase 1...

Non-communicable diseases in Lebanon: results from World Health Organization STEPS survey 2017.

Sep 21, 2020

Non-communicable diseases (NCDs) are a major global health problem. The objective of the study was to estimate the prevalence of common risk factors for NCDs in Lebanon, both among the Lebanese popula...

Probiotic-enriched milk and dairy products increase gut microbiota diversity: a comparative study.

Sep 21, 2020

Targeting gut microbiota with probiotics has emerged as a promising nutritional approach for the prevention of obesity and metabolic syndrome. Cultured dairy products can be effectively employed for t...

Underuse of oral anticoagulants in privately insured patients with atrial fibrillation: A population being targeted by the IMplementation of a randomized controlled trial to imProve treatment with oral AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AFib).

Sep 21, 2020

Many studies showing underuse of oral anticoagulants (OACs) in patients with atrial fibrillation (AF) predated the advent of the non-vitamin K antagonist OACs. We retrospectively examined use of OACs ...

Increasing age and non-liver comorbidities in patients with chronic hepatitis B in Taiwan: A nationwide population-based analysis.

Sep 17, 2020

Data from the US suggest that chronic hepatitis B (CHB) patients have aged in the past decade. However, the burden of non-liver comorbidities have not been well characterized in Taiwan, where CHB is v...

How Much Weight Loss is Required for Cardiovascular Benefits? Insights From a Metabolic Surgery Matched-cohort Study.

Sep 17, 2020

The aim of this study was to determine the minimum amount of weight loss required to see a reduction in major adverse cardiovascular events (MACE).Although obesity is an established risk factor for mo...

Incidence of type 1 diabetes by socio-demographic characteristics among South Australian children: Whole-of-population study.

Sep 17, 2020

To describe and compare the incidence of type 1 diabetes (T1D) in South Australia by individual and area-level socio-economic characteristics among children aged ≤11 years.This is a whole-of-popul...