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Diabetes

Step Count Associations Between Adults at Risk of Developing Diabetes and Their Children: The Feel4Diabetes Study.

Mar 15, 2021

Shared risk factors of type 2 diabetes mellitus (T2DM) between parents at risk and their children, such as low physical activity levels, should be addressed to prevent the development of the disease. ...

Painful diabetic neuropathy is associated with increased nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.

Mar 15, 2021

Painful diabetic peripheral neuropathy (pDPN) is associated with small nerve fiber degeneration and regeneration. This study investigated whether the presence of pDPN may influence nerve regeneration ...

Improved Postprandial Glucose Control With Ultra Rapid Lispro Versus Lispro With Continuous Subcutaneous Insulin Infusion in Type 1 Diabetes: PRONTO-Pump-2.

Mar 11, 2021

To evaluate the efficacy and safety of ultra rapid lispro (URLi) versus lispro in persons with type 1 diabetes on continuous subcutaneous insulin infusion (CSII).This was a phase 3, 16-week, treat-to-...

Fasting and Postprandial Plasma Glucose Contribution to HbA1c and Time in Range in People with Type 2 Diabetes on Basal and Bolus Insulin Therapy: Results from a Pooled Analysis of Insulin Lispro Clinical Trials.

Mar 11, 2021

As more innovative insulin therapies become available, it is necessary to better understand the interrelations between glycaemic metrics of fasting plasma glucose (FPG), postprandial glucose (PPG), Hb...

Factors associated with knowledge of the disease in people with type 2 diabetes mellitus.

Mar 11, 2021

To identify factors associated with the level of knowledge of the disease in people with type 2 Diabetes.A cross-sectional study carried out with 412 people with diabetes registered in the Primary Hea...

Expression of MicroRNAs (miR-15b, miR-16, miR-138, miR-221, and miR-222) as Biomarkers of Endothelial Corpus Cavernosum Dysfunction in a Diabetic Alcoholic Murine Model.

Mar 08, 2021

MicroRNAs (miRNAs) are short noncoding RNA molecules that regulate gene expression and are related to endothelial dysfunction (EnD). Recently, miRNAs have also been explored as potential biomarkers an...

Antioxidative and antidiabetic effects of Capparis spinosa fruit extract on high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats.

Mar 08, 2021

Capparis spinosa (CS) is known as a hypoglycemic medication in many countries. This study was designed to reveal the protective effects of the hydro-ethanolic extract of CS (HECS) fruit against diabet...

The carbon isotope ratios of nonessential amino acids identify sugar-sweetened beverage (SSB) consumers in a 12-wk inpatient feeding study of 32 men with varying SSB and meat exposures.

Mar 08, 2021

The carbon isotope ratios (CIRs) of individual amino acids (AAs) may provide more sensitive and specific biomarkers of sugar-sweetened beverages (SSBs) than total tissue CIR. Because CIRs turn over sl...

Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice.

Mar 01, 2021

Type 2 Diabetes mellitus (T2DM) has become a major public health issue associated with a high risk of late-onset Alzheimer's disease (LOAD). Mitochondrial dysfunction is one of the molecular events th...

Advanced finger infection: more frequent than expected and mostly iatrogenic.

Mar 01, 2021

Some patients present at an advanced stage of their fingertip infection with an extension of the infection in anatomical spaces or into fragile structures. One hundred and twenty-five patients have be...

Mechanisms of COVID-19 Entry into the Cell: Potential Therapeutic Approaches Based on Virus Entry Inhibition in COVID-19 Patients with Underlying Diseases.

Mar 01, 2021

The Coronavirus disease 2019 (COVID-19) virus spread from Wuhan, China, in 2019 and is spreading rapidly around the world. COVID-19 victims are almost associated with cardiovascular disease, high bloo...

Obstructive sleep apnoea in adult patients post-tonsillectomy.

Jan 18, 2021

The impact of removing the upper airway lymphoid tissue and in particular, tonsillectomy, in adults with OSA has not been demonstrated in large populations.To compare the severity of OSA and the preva...

Risk factors of orbital complications in outpatients presenting with severe rhinosinusitis: a case-control study.

Jan 18, 2021

We assessed associations of potential factors with orbital complications in acute rhinosinusitis (ARS) patients.An unmatched case-control study SETTING: A tertiary referral hospital in Thailand PARTIC...

Olanzapine-induced insulin resistance may occur via attenuation of central K channel-activation.

Jan 14, 2021

Antipsychotic use is associated with an increased risk of type 2 diabetes. Recent work suggests antipsychotics can induce insulin resistance immediately and independently of weight gain, and that this...

Ameliorative effects of endurance training and Matricaria chamomilla flowers hydroethanolic extract on cognitive deficit in type 2 diabetes rats.

Jan 14, 2021

Diabetes mellitus is mainly associated with degeneration of the central nervous system, which eventually leads to cognitive deficit. Although some studies suggest that exercise can improve the cogniti...

Silk fibroin/poly-(L-lactide-co-caprolactone) nanofiber scaffolds loaded with Huangbai Liniment to accelerate diabetic wound healing.

Jan 14, 2021

Diabetic infection is a long-term complication difficult to cure. The skin of diabetic patients is prone to damage, the healing is slow after the injury, and the wound occurs repeatedly. Therefore, th...

ENVINT-D-20-01309: Long-term exposure to air pollution, road traffic noise, residential greenness, and prevalent and incident metabolic syndrome: Results from the population-based KORA F4/FF4 cohort in Augsburg, Germany.

Jan 11, 2021

A growing number of epidemiological studies show associations between environmental factors and impaired cardiometabolic health. However, evidence is scarce concerning these risk factors and their imp...

A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis.

Jan 11, 2021

Fibroblast growth factor 21 (FGF21) has become a promising therapeutic target for metabolic diseases such as type 2 diabetes (T2D), obesity and non-alcoholic steatohepatitis. However, the clinical app...

A multi-omics view of the complex mechanism of vascular calcification.

Jan 07, 2021

Vascular calcification is a high incidence and high risk disease with increasing morbidity and high mortality, which is considered the consequence of smooth muscle cell transdifferentiation initiating...

New insight into the role of isorhamnetin as a regulator of insulin signaling pathway in type 2 diabetes mellitus rat model: Molecular and computational approach.

Jan 07, 2021

We intended to examine the molecular mechanism of action of isorhamnetin (IHN) to regulate the pathway of insulin signaling. Molecular analysis, immunofluorescence, and histopathological examination w...