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Diabetes

[Alpha-1 antitrypsin deficiency: cause and cofactor for liver disease].

Jun 03, 2021

Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder arising due to mutation in alpha1-antitrypsin (AAT). AAT mutations interfere with the AAT production/secretion, cause decreased AAT serum le...

Reactions of older Swiss adults to the COVID-19 pandemic: A longitudinal survey on the acceptance of and adherence to public health measures.

May 31, 2021

An important public health strategy during the COVID-19 pandemic was the protection of people at risk of severe progressions of an infection; namely, older people and people with pre-existing conditio...

Glycolipid toxicity induces osteogenic dysfunction via the TLR4/S100B pathway.

May 31, 2021

Diabetes can cause bone metabolism disorders and osteoporosis. The occurrence of both diabetes mellitus and osteoporosis increases the disability and mortality of elderly individuals due to pathologic...

Screening for Diabetes Mellitus and Hypertension in Ile-Ife - A World Diabetes Day Experience.

May 31, 2021

Non-communicable diseases have emerged as major public health concerns in developing nations, where communicable diseases used to be the major contributor to the public health burden. Diabetes and hyp...

Responding to Discriminatory Patient Requests.

May 27, 2021

Julia is a 13-year-old White adolescent girl who was referred for psychological counseling given concerns related to mood, nonadherence, and adjustment secondary to her new diagnosis of type 1 diabete...

Evaluation of Meal Carbohydrate Counting Errors in Patients with Type 1 Diabetes.

May 27, 2021

Correct estimation of meal carbohydrate content is a prerequisite for successful intensified insulin therapy in patients with diabetes. In this survey, the counting error in adult patients with type 1...

Acute Respiratory Distress Syndrome (ARDS) after trauma: Improving incidence, but increasing mortality.

May 24, 2021

Acute Respiratory Distress Syndrome (ARDS) is an infrequent, yet morbid inflammatory complication in injury victims. With the current project we sought to estimate trends in incidence, determine outco...

The prevalence of frailty among community-dwelling older adults with diabetes: A meta-analysis.

May 24, 2021

Coexistence of frailty and chronic diseases including diabetes is related to a higher risk of adverse health outcomes. There is an increasing interest in the intersection of diabetes and frailty. Unde...

Tween 20-capped gold nanoparticles for selective extraction of free low-molecular-weight thiols in saliva followed by capillary electrophoresis with contactless conductivity detection.

May 24, 2021

Low-molecular-weight thiols are widely present in human fluids, and are regarded as a kind of potential broad-spectrum evaluation indicators for some clinical diseases. In this work, gold nanoparticle...

The effect of diet change and insulin dysregulation on the fecal microbiome of ponies.

May 20, 2021

The equine microbiome can change in response to dietary alteration and might play a role in insulin dysregulation. The aim of this study was to determine the effect of adding pasture to a hay diet on ...

Network analysis reveals important genes in human placenta.

May 20, 2021

To determine which genes are important in placenta by network analysis.Placenta expressing genes were screened from RNA-Seq data. Protein-protein interaction data were downloaded from STRING (v11.0) d...

Effect of Vitamin D status on QTc interval in type 2 diabetes mellitus.

May 20, 2021

Diabetes mellitus (DM) is associated with autonomic neuropathy and metabolic abnormalities. These predispose the patients to prolongation of QTc and risk of arrhythmias and sudden cardiac death. Vitam...

The therapeutic role of lactobacillus and montelukast in combination with metformin in diabetes mellitus complications through modulation of gut microbiota and suppression of oxidative stress.

May 17, 2021

Male reproductive dysfunction is one of the overlooked findings of diabetes mellitus (DM) that deserves greater scientific attention. This study is designed to explore the therapeutic potential of met...

Diabetic Oculomotor Nerve Palsy Displaying Enhancement of the Oculomotor Nerve in the Orbit and Cavernous Sinus on MRI.

May 13, 2021

Imaging data were scarce on diabetic oculomotor nerve palsy (ONP). Our study explored the MRI features and their clinical implications for diabetic ONP.Fifty-nine patients with a clinical diagnosis of...

Leveraging Artificial Intelligence to Improve Chronic Disease Care: Methods and Application to Pharmacotherapy Decision Support for Type-2 Diabetes Mellitus.

May 13, 2021

 Artificial intelligence (AI), including predictive analytics, has great potential to improve the care of common chronic conditions with high morbidity and mortality. However, there are still many c...

Metabolic risk factors, genetic predisposition, and risk of severe liver disease in Chinese: a prospective study of 0.5 million people.

May 10, 2021

Metabolic risk factors have been shown to be associated with severe liver disease (SLD) in Chinese populations. However, there is limited evidence on the combined impact of these factors, or the genet...

The associations between individual plasma SFAs, serine palmitoyl-transferase long-chain base subunit 3 gene rs680379 polymorphism, and type 2 diabetes among Chinese adults.

May 10, 2021

Several individual studies have shown that circulating levels of odd-chain SFAs and very-long-chain SFAs (VLSFAs) may have beneficial effects, but the results are mixed. While the dietary and metaboli...

Indications for Maternal Echocardiography in Detecting Disease and the Impact on Pregnancy Management.

May 06, 2021

Few obstetric-specific guidelines detail the indications for screening echocardiography in pregnancy. The objective of the study is to examine the association of common indications for maternal echoca...

Prevalence of sarcopenic obesity and association with metabolic syndrome in an adult Iranian cohort: The Fasa PERSIAN cohort study.

May 06, 2021

Sarcopenic obesity (SO) is characterised by a concomitant high fat mass (FM) and low fat free mass (FFM) leading to an increased cardio-metabolic risk. This analysis aims to estimate the SO prevalence...

Hydro-alcoholic extract of reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and analysis.

May 06, 2021

1-Deoxynojirimycin (1-DNJ), the main active component found in () is reported to be effective in controlling diabetes. We have evaluated the effect of hydro-alcoholic extract of leaves on the fastin...