Company Pulls ‘One Chip Challenge’ From Store Shelves After Teen Dies
FRIDAY, Sept. 8, 2023 (HealthDay News) — The maker of the “One Chip Challenge”...
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Company Reaches $479 Million Settlement Over Defects in CPAP Machines
FRIDAY, Sept. 8, 2023 (HealthDay News) — Philips Respironics has agreed to a partial $479...
Read MoreSynergistic effects of BTN3A1, SHP2, CD274, and STAT3 gene polymorphisms on the risk of systemic lupus erythematosus: a multifactorial dimensional reduction analysis.
Systemic lupus erythematosus is a complex autoimmune disorder, and evidence supports the significance of genetic polymorphisms in SLE genetic susceptibility. The aim of this study was to assess the effects of BTN3A1...
Read MoreA prognostic model for systemic lupus erythematosus-associated pulmonary arterial hypertension: CSTAR-PAH cohort study.
Pulmonary arterial hypertension is a major cause of death in systemic lupus erythematosus, but there are no tools specialized for predicting survival in systemic lupus erythematosus-associated pulmonary arterial hypertension.To...
Read MoreFactors associated with mental health outcomes after COVID-19: A 24-month follow-up longitudinal study.
Investigate the proportion of mental health outcomes (MHOs) and associated factors in COVID-19 survivors during a 24-month follow-up period.An observational, prospective study was performed in a teaching hospital in...
Read MoreAncient dormant virus remnant ERVW-1 drives ferroptosis via degradation of GPX4 and SLC3A2 in schizophrenia.
Human endogenous retroviruses (HERVs) are remnants of retroviral infections in human germline cells from millions of years ago. Among these, ERVW-1 (also known as HERV-W-ENV, ERVWE1, or ENVW) encodes the envelope protein of the...
Read MoreMarkers of community outbreak and facility type for mitigation of COVID-19 in long-term care homes in Ontario, Canada: insights and implications from a time-series analysis.
The resident deaths among Long Term Care Home (LTCH) accounted for more than 65% of total deaths in the province of Ontario, Canada, during March 29 to June 3, 2020, yet not all LTCHs were severely affected.We carried out a...
Read MoreThe COVID-19 pfizer BioNTech mRNA vaccine and the frequency of seizures.
A nationwide vaccination operation against Coronavirus disease 2019 (COVID-19) using the BNT162b2 mRNA vaccine commenced in Israel in December 2020. People older than 60 were prioritized, and most were vaccinated shortly after....
Read MoreWhat to improve: results of fixed-hinge knee endoprosthesis reconstructions over 40 years in a single tumor center.
Over the past decades, numerous structural changes in implants, medical treatments, and surgical technics have been made for Malignant Bone Tumors (MBT) around the knee. However, the overall care improvement is still unclear....
Read MoreIntegrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation.
As the second leading cause of death for cancer among men worldwide, prostate cancer (PCa) prevention and detection remain a critical challenge. One aspect of PCa research is the identification of common environmental agents...
Read MorePlasma levels of 12 different cytokines correlate to PD-1 inhibitor combined chemotherapy responses in advanced non-small-cell lung cancer patient.
Targeted anti-programmed death receptor 1 (PD-1) monoclonal antibodies, when combined with chemotherapy, have shown improved outcomes in non-small cell lung cancer (NSCLC). However, it is important to note that not all patients...
Read MoreExosome-derived miR-372-5p promotes stemness and metastatic ability of CRC cells by inducing macrophage polarization.
Colorectal cancer (CRC) is the most common malignancy in the digestive system, and tumor metastasis is the main cause of death in clinical patients with CRC. It has been shown that exosomes promote phenotypic changes in...
Read MoreEnsitrelvir eradicates persistent SARS-CoV-2 infection in a follicular lymphoma patient treated with anti-CD20 antibodies.
Patients with hematological malignancies, especially B-cell malignancies, who received anti-CD20 antibodies exhibit a poor immune response to the mRNA coronavirus disease 2019 (COVID-19) vaccine within 6-12 months after the last...
Read MoreGalactomannan polysaccharide as a biotemplate for the synthesis of zinc oxide nanoparticles with photocatalytic, antimicrobial and anticancer applications.
Bio-templates provide a facile, rapid, and environmentally benign route for synthesizing various nanostructured materials. Herein, Locust Bean Gum (LBG), a galactomannan polysaccharide, has been used as a biotemplate for...
Read MoreMortality associated with bacterial and fungal infections and overdose among people with drug use diagnoses.
Hospital visits for drug use-related bacterial and fungal infections have increased alongside overdose deaths. The incidence of mortality from these infections and the comparison to overdose mortality is not established.This...
Read MoreAssociation Between Falls, Head Impacts, and Mortality Among Older Adults in Long-Term Care.
Residents in long-term care (LTC) are at high risk for falls, and falls in LTC often result in impact to the head, with clinical consequences that may be challenging to detect. We examined whether the survival of LTC residents...
Read MoreInhibition of influenza a virus infection by natural stilbene piceatannol targeting virus hemagglutinin.
Given the magnitude of influenza pandemics as a threat to the global population, it is crucial to have as many prevention and treatment options as possible. Piceatannol (PIC) is a tetrahydroxylated stilbenoid...
Read MoreReport of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development.
The National Center for Advancing Translational Sciences (NCATS) Assay Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development, held virtually on 7-8 June 2022, provided comprehensive coverage of...
Read MoreSmall airway disease in post-acute COVID-19 syndrome, a non-conventional approach in three years follow-up of a patient with long COVID: a case report.
Small airways disease (SAD), a novel finding described in post-acute COVID-19 patients, should be suspected when respiratory symptoms continue, air trapping persists on expiratory CT scans, and imaging findings fail to improve...
Read MoreCOVID-19 vaccine safety in Scotland – background rates of adverse events of special interest.
Mass COVID-19 vaccination commenced in December 2020 in Scotland. Monitoring vaccine safety relies on accurate background incidence rates (IRs) for health outcomes potentially associated with vaccination. This study aimed to...
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