B cell clonal expansion and convergent antibody responses to SARS-CoV-2.
During virus infection B cells are critical for the production of antibodies and protective...
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Allergy & Immunology General
Extensive pneumorrhachis after spontaneous pneumomediastinum : A case report.
Pneumorrhachis is the presence of air within the spinal canal and is most often traumatic or...
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Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma.
A challenge in the post-GWAS era is to assign function to disease-associated variants. However,...
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Functional basis for dose-dependent antagonism of rat and rabbit neuromuscular transmission by the bis-pyridinium oxime MMB4.
Organophosphorus (OP) compounds inhibit central and peripheral acetylcholinesterase (AChE)...
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A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig.
Animal models are extensively used to study underlying mechanisms in asthma. Guinea pigs share...
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Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.
The upper airways present a barrier to inhaled allergens and microbes, which alter immune...
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Investigating asthma heterogeneity through shared and distinct genetics: insights from genome-wide cross-trait analysis.
Asthma is a heterogeneous respiratory disease reflecting distinct pathobiological mechanisms....
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The predicative clinical features associated with chronic cough that has a single underlying cause.
Few studies have investigated the usefulness of the clinical characteristics of cough in the...
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Biomarkers of type 2 airway inflammation as predictors of loss of asthma control during step-down therapy for well-controlled disease: The Long Acting Beta Agonist Step-down Study (LASST).
Biomarkers that can predict loss of asthma control among patients being considered for step-down...
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High discontinuation rates of peroral ASA treatment for CRSwNP. A real-world multi-center study of 171 N-ERD patients.
Non-steroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease (N-ERD) consists of...
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Perioperative and Long-Term Outcomes After Thoracoabdominal Aortic Aneurysm Repair of Chronic Dissection Etiology.
Open repair of thoracoabdominal aortic aneurysms (TAAA) that have developed secondary to chronic...
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Modifiable lifestyle factors and heart failure: A Mendelian randomization study.
Lifestyle factors may be important targets in the prevention of heart failure. The current...
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Smoking cessation prolongs survival in female cancer survivors – the Danish nurse cohort.
To explore smoking cessation between cancer survivors and cancer-free women, and the potential...
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Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy.
The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for...
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What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?
As the lung develops, epithelial-mesenchymal crosstalk is essential for the developmental...
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Sleep Duration Patterns from Adolescence to Young Adulthood and the Risk of Asthma.
This study examined the association between sleep duration trajectories from adolescence to young...
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Ophthalmic corticosteroids in pregnant women with allergic conjunctivitis and adverse neonatal outcomes: propensity score analyses.
The risks of topical ophthalmic corticosteroids during pregnancy remain unclear. We investigated...
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Meibomian gland dysfunction is the primary determinant of dry eye symptoms: Analysis of 2346 patients.
To determine relative contributions of various ocular surface clinical signs and predisposing...
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Medical data science in rhinology: Background and implications for clinicians.
An important challenge of big data is using complex information networks to provide useful...
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Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality.
In vivo transposon mutagenesis, coupled with deep sequencing, enables large-scale genome-wide...
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