Structural isomers of saligenin-based β2-agonists: synthesis and insight into the reaction mechanism.
Salmeterol and albuterol are well-known β2-adenoreceptor agonists widely used in the treatment of...
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Allergy & Immunology General
Biseugenol Exhibited Anti-Inflammatory and Anti-Asthmatic Effects in an Asthma Mouse Model of Mixed-Granulocytic Asthma.
In the present work, the anti-inflammatory and antiasthmatic potential of biseugenol, isolated as...
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Airway Epithelial Dysfunction in Asthma: Relevant to Epidermal Growth Factor Receptors and Airway Epithelial Cells.
Airway epithelium plays an important role as the first barrier from external pathogens, including...
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Riparin II potentials the effect of ephedrine on inflammation and remodelling in the airway of rats suffering from asthma by regulating transforming growth factor-β/Smad3 signalling pathway.
Asthma is a chronic obstructive lung disorder involving hyperresponsive lung tissue. This study...
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The effect of a low-nickel diet and nickel sensitization on gastroesophageal reflux disease: A pilot study.
Gastroesophageal reflux disease (GERD) is a common medical condition, frequently refractory to...
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Artificial intelligence in the diagnosis of pediatric allergic diseases.
Artificial intelligence (AI) is a field of data science pertaining to advanced computing machines...
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Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.
With the growth of monoclonal antibodies and other proteins as major modalities in the...
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Remission and changes in severity over 30 years in an adult asthma cohort.
Long-term follow-up studies of adults with well-characterised asthma are sparse.We aimed to...
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Pancreatic neuroendocrine tumor presenting in indolent systemic mastocytosis: A case report.
Systemic mastocystosis, a disorder of clonal mast cell expansion presents with symptoms of...
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Erenumab-Induced Severe Nausea Leading to Smoking Cessation: A Retrospective Case Series.
Erenumab is a novel treatment modality with a relatively benign and safe side effect profile,...
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Clinical and biological factors associated with irreversible airway obstruction in adult asthma.
Airway remodeling, as many other factors, may lead to lung function decline and irreversible...
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Acute arterial occlusion of the lower limb as the main clinical manifestation in a patient with Covid-19 – Case Report.
COVID-19 infection may predispose to venous and arterial thromboembolism due to excessive...
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Risk factors and association with severity of keratoconus: the Australian study of Keratoconus.
Our results show that asthmatic patients tend to have more severe KC and thus close monitoring for...
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Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time.
Levels of cytokines are used for in-depth characterization of patients with asthma; however, the...
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AlgPred 2.0: an improved method for predicting allergenic proteins and mapping of IgE epitopes.
AlgPred 2.0 is a web server developed for predicting allergenic proteins and allergenic regions in...
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Occurrence of milk and egg allergens in foodstuffs in Canada.
Food allergies are life-threatening conditions that allergic individuals can avoid by consulting...
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A study of longitudinal mobile health data through fuzzy clustering methods for functional data: The case of allergic rhinoconjunctivitis in childhood.
The use of mobile communication devices in health care is spreading worldwide. A huge amount of...
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Clinical pharmacokinetics and pharmacodynamics of cerliponase alfa, enzyme replacement therapy for CLN2 disease by intracerebroventricular administration.
Cerliponase alfa is recombinant human TPP1 delivered by intracerebroventricular (ICV) infusion for...
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Novel Framework for Measuring Whole Knee Osteoarthritis Progression Using Magnetic Resonance Imaging.
We developed and validated a set of composite scores that combine quantitative magnetic resonance...
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Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor.
Somatic mutations of calreticulin (CALR)have been identified as one of the main disease drivers of...
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