Low threshold for cutaneous allergen sensitization but no spontaneous dermatitis or atopy in filaggrin-deficient mice.
Loss of filaggrin (FLG) causes Ichthyosis vulgaris. Reduced filaggrin expression compromises...
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Allergy & Immunology General
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease.
Asthma (chronic allergic airways disease, AAD) is characterized by airway inflammation (AI),...
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Impact of Rapid Transition to Telemedicine-Based Delivery on Allergy/Immunology Care during COVID-19.
COVID-19 necessitated widescale adoption of telemedicine (TM) and restriction of in-person care....
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Immune dysregulation in human ITCH deficiency successfully treated with hematopoietic cell transplantation.
Mutations in ITCH, which encodes an E3 ubiquitin-protein ligase, can result in systemic...
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Vitamin D deficiency and lung function decline in healthy individuals: A large longitudinal observation study.
A reliable evidence from a comprehensive large-scale study supporting associations between serum...
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Development and validation of a risk prediction model for high-risk adenomas at the time of first screening colonoscopy among screening aged Canadians.
The aim of this study was to develop a risk prediction model for HRAs detected at screening...
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Impact of human rhinoviruses on gene expression in pediatric patients with severe acute respiratory infection.
Human rhinovirus (HRV) is one of the most common viruses, causing mild to severe respiratory tract...
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Preventing sepsis; how can artificial intelligence inform the clinical decision-making process? A systematic review.
Sepsis is a life-threatening condition that is associated with increased mortality. Artificial...
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Heightened respiratory-parasympathetic coupling to airways in the spontaneously hypertensive rat.
Carotid bodies (CBs) chemoreceptors are hyperactive in hypertension, and their acute activation...
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4-CMTB Ameliorates Ovalbumin-Induced Allergic Asthma through FFA2 Activation in Mice.
Free fatty acid receptor 2 (FFA2, also known as GPR43), a G-protein-coupled receptor, has been...
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Health-related quality of life in children at the diagnosis of Vernal Keratoconjunctivitis.
Vernal keratoconjunctivitis (VKC) is a bilateral, chronic, allergic condition mostly affecting...
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Development of Anti-Mouse CC Chemokine Receptor 3 Monoclonal Antibodies for Flow Cytometry.
CC chemokine receptor 3 (CCR3), also known as CD193, belongs to class A of G protein-coupled...
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Tectochrysin ameliorates murine allergic airway inflammation by suppressing Th2 response and oxidative stress.
Tectochrysin, a flavonoid compound, can be isolated from propolis, Alpinia oxyphylla Miq, and...
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A Mobile Health Intervention to Increase Physical Activity in Pulmonary Arterial Hypertension.
Supervised exercise training improves outcomes in patients with pulmonary arterial hypertension...
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Elastase Activity from Pseudomonas aeruginosa Respiratory Isolates and ICU Mortality.
Pseudomonas aeruginosa (PA) is a common cause of respiratory infection and morbidity. Pseudomonas...
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Effects of different detergent-containing children’s toothpastes on the viability, osteogenic and chondrogenic differentiation of human dental periodontal ligament stem cells and gingival stem cells in vitro.
Detergents are the most commonly used compounds in toothpastes due to their foaming and cleaning...
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The Asthma Toolkit Bootcamp to Improve Rural Primary Care for Pediatric Asthma.
Children with asthma living in rural areas receive most of their care from primary care providers...
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Estimated Glomerular Filtration Rate (eGFR) based on cystatin C was associated with increased risk of hip and proximal humerus fractures in women and decreased risk of hip fracture in men, whereas eGFR based on creatinine was not associated with fracture risk in both sexes: The Tromsø Study.
Patients with end-stage kidney disease have an increased fracture risk. Whether mild to moderate...
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Equine respiratory viruses, airway inflammation and performance in thoroughbred racehorses.
Equine asthma is a common cause of poor performance in racehorses but it is unclear if respiratory...
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Sleep disturbance in adult dermatological patients: A cross-sectional study on prevalence, burden and associated factors.
Sleep disturbance remains insufficiently characterized in many dermatoses.To investigate the...
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