Adding a Kinase to Pembrolizumab May Increase CLL Treatment Efficacy
Adding BCR kinase inhibitor ibrutinib or idelalisib to monoclonal antibody pembrolizumab increases treatment efficacy in CLL with Richter transformation.
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Author: Teresa Sellinger
Efficacy and Safety of Nipocalimab in Sjögren’s Disease: Phase 2 Trial Results
Nipocalimab showed a significant decrease in Clinical European League Against Rheumatism Sjögren’s Syndrome Disease Activity Index.
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Early Treatment With Ambrisentan Prevents PAH Development in Patients With SSc
In SSc plus mild pulmonary vascular disease, early treatment with ambrisentan effectively prevented pulmonary vascular disease progress and development of PAH.
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Upadacitinib Show Promise for Treatment of Giant Cell Arteritis
Upadacitinib 15 mg demonstrated convincing results as a treatment for giant cell arteritis in the phase 3 SELECT-GCA trial.
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Real-World Comparative Effectiveness of Advanced Therapies in Psoriatic Arthritis
PRO-SPIRIT study examines the real-world efficacy results of disease-modifying antirheumatic drugs for patients with psoriatic arthritis.
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Key Predictors of Rheumatoid Arthritis Flares Identified
Baseline methotrexate use has been found to be able to predict remission flare ups in patients with rheumatoid arthritis.
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Anti-Ro/SSA Antibodies in Systemic Sclerosis: a Novel Predictor of Severe Lung Involvement
Research suggests including anti-SSA antibodies in routine clinical practice could notably improve the risk stratification of patients with SSc
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Dual IL-17 Blocker Significantly Reduces Spinal Radiographic Progression in R-axSpA
Bimekizumab has been found to minimize spinal radiographic progression in patients with radiographic axial spondyloarthritis.
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Molecular Testing Appears To Be Increasing in eNSCLC
An increasing number of patients with eNSCLC currently have access to biomarker testing and targeted therapies, according to the MYLUNG consortium.
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Spotlight On the 42nd ASRS Annual Scientific Meeting July 17-20
Immerse yourself in retinal science advancements, therapeutics, innovation and fellowship at the 42nd ASRS Annual Scientific Meeting July 17-20, 2024.
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Achilles Tendon Involvement in PsA Linked to Persistent Pain and Severe Functional Impairment
Structural and functional differences in the Achilles tendon could be clinically relevant when managing pain in patients with psoriatic arthritis.
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Zanubrutinib Plus Venetoclax Shows Promise in Del(17p)/TP53-Mutated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Zanubrutinib plus venetoclax delivered promising preliminary efficacy results in newly diagnosed CLL/SLL in participants with del(17p) and/or TP53 mutations.
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Mosunetuzumab Benefits Outcomes Across Follicular Lymphoma Subgroups
Patients with pre-treated relapsed or refractory follicular lymphoma have shown benefits with mosunetuzumab.
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Promising Results for Anitocabtagene Autoleucel Therapy in Multiple Myeloma
Anitocabtagene autoleucel therapy showed promising results in patients with relapsed or refractory multiple myeloma.
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Revumenib Displays Encouraging Anti-Tumor Activity in KMT2Ar Acute Leukemia, AUGMENT-101 Trial Stopped Early
The AUGMENT-101 trial in patients with in KMT2Ar leukemia has been stopped early because of revumenib encouraging anti-tumor activity.
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Is Pelabresib + Ruxolitinib the Paradigm-Shifting Combo Therapy for Myelofibrosis?
Pelabresib plus ruxolitinib has shown efficacy in the treatment responses of patients with myelofibrosis.
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Sovleplenib Delivers Durable Responses and QOL Improvements in Primary Immune Thrombocytopenia
Sovleplenib may offer QOL improvements for patients with primary immune thrombocytopenia.
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Multiple Novel Oral Agents Show Promise in Psoriasis
Oral agents have show good efficacy results in patients with psoriasis. An oral agent is also easier for patients to intake then other forms of medication.
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The Unfavorable Role of Obesity in Psoriatic Disease
The association between obesity and psoriatic disease. Smoking, genetics, as well as obesity, all potentially contribute to the development of psoriasis in all age groups.
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Depression Complicates Management of Psoriatic Disease
In a new study, researchers explore the relationship between psoriasis and depression, and how depression can be addressed with different forms of therapy.
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