Author: Janine Anthes
Highlights from ASCO 2021: Leukemia – eBook
Jul 23, 2021
ASCO Leukemia Annual Meetingv3 Featuring… ELEVATE-RR: Acalabrutinib demonstrates similar...
Read MorePW Podcast: Will there be a COVID-19 “Olympic Variant”?
Jul 21, 2021
In an interview with Physician’s Weekly, Annie Sparrow, MD, Special Advisor to the...
Read MoreEarly-Stage NSCLC: Promising Data for Neoadjuvant Durvalumab with Stereotactic Body Radiotherapy
Jul 16, 2021
A recently published phase 2 study in Lancet Oncology showed that the combination of neoadjuvant durvalumab with stereotactic body radiotherapy (SBRT) is safe and grants a nearly 55% major pathologic response rates among...
Read MorePhysQuiz: A Focus on Tardive dyskinesia
Jul 15, 2021
Are you caught up on what’s happening on advancements in managing tardive dyskinesia? Test...
Read MoreT-DXd Combinations in HER2-positive Metastatic Breast Cancer
Jul 14, 2021
The DESTINY-Breast07 trial will test trastuzumab deruxtecan (T-DXd) combinations in patients with HER2-positive advanced or metastatic breast cancer, as a phase 1b/2, open-label, multicenter, dose-finding and dose-expansion...
Read MoreELEVATE-RR: Acalabrutinib demonstrates similar efficacy and better safety compared with ibrutinib
Jul 14, 2021
The phase 3 ELEVATE-RR trial was a head-to-head comparison of acalabrutinib versus ibrutinib in previously treated patients with chronic lymphocytic leukemia. The first results of this study demonstrated that acalabrutinib had...
Read MoreELEVATE-TN: long-term efficacy in chronic lymphocytic leukemia
Jul 14, 2021
Acalabrutinib with or without obinutuzumab demonstrated superior long-term efficacy over obinutuzumab + chlorambucil in patients with chronic lymphocytic leukaemia (CLL). Results from the 4-year follow-up of the ELEVATE-TN study...
Read MoreDurvalumab after chemoradiation proven safe in elderly NSCLC patients
Jul 14, 2021
The addition of durvalumab after chemoradiation (CRT) in unresectable stage 3 non-small cell lung cancer (NSCLC) can be safely delivered in elderly patients ≥70 years with comparable improvement in overall survival (OS), as...
Read MoreDoubling overall survival in US veterans with stage 3 non-small cell lung cancer
Jul 14, 2021
Median overall survival doubled for veterans with stage 3 non-small cell lung cancer who received chemoradiotherapy plus durvalumab, as compared to those receiving chemoradiotherapy alone, according to a new study presented at...
Read MorePreventing interstitial lung disease in patients on trastuzumab detruxtecan
Jul 14, 2021
Results from the phase 2 clinical trial DESTINY-Breast01 showed that the investigational human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate [Fam-] trastuzumab deruxtecan (T-DXd) has durable...
Read MoreThe Importance & Power of Physicians Advocating for Themselves
Jul 13, 2021
In the past, we as physicians have not done a great job of advocacy, and we have largely been removed from policy discussions. The emergence of physician advocacy is a relatively new phenomenon. Why? … Read Full Article...
Read MoreT-DXd Response on Brain Mets HER2+ Breast Cancer
Jul 8, 2021
Results from the phase 2 clinical trial DESTINY-Breast01 showed that the investigational human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate [Fam-] trastuzumab deruxtecan (T-DXd) has just as durable...
Read More5-year PACIFIC data hold strong in NSCLC
Jul 8, 2021
Updated findings of the PACIFIC trial showed an overall survival (OS) rate of 43% after 5 years of treatment with durvalumab, which has . Physician’s Weekly spoke with Dr. Camille Hertzka, vice president and head of Oncology, US...
Read MoreThe EFFORT needed to overcome PARP resistance in ovarian cancer
Jul 8, 2021
Adavosertib with or without olaparib demonstrated clinical activity with a manageable toxicity...
Read MoreThe Placebo Effect
Jul 7, 2021
“He was unhappy to learn that I had prescribed a placebo, but when I told him it was an...
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