Revising Pooled Cohort Equations Improves CVD Risk Prediction
Use of updated equations would relabel about 11.8 million high-risk U.S. adults as lower-risk
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Use of updated equations would relabel about 11.8 million high-risk U.S. adults as lower-risk
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Adaptive transfer of mutant-protein-specific tumor-infiltrating lymphocytes leads to disease regression
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Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival
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Similar efficacy for endocrine, chemoendocrine tx for women with midrange 21-gene recurrence score
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And, pre-op chemoradiotherapy linked to longer overall survival than immediate surgery
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The New England journal of medicine 2018 05 22() doi 10.1056/NEJMoa1803538 Abstract Background We hypothesized that fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) would be superior to medical...
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The New England journal of medicine 2018 05 21() doi 10.1056/NEJMoa1804093 Abstract Background Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13...
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The New England journal of medicine 2018 05 21() doi 10.1056/NEJMoa1804092 Abstract Background Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13...
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Current biology : CB 2018 05 1728(11) 1714-1724.e4 pii 10.1016/j.cub.2018.04.015 Abstract Intermittent fasting (IF) can improve function and health during aging in laboratory model organisms, but the mechanisms at work await...
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Surgical neurology international 2018 04 269() 91 doi 10.4103/sni.sni_45_18 Abstract Background Numerous physical, psychological, and emotional benefits have been attributed to marijuana since its first reported use in 2,600 BC...
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Journal for immunotherapy of cancer 2018 05 166(1) 39 doi 10.1186/s40425-018-0349-3 Abstract Immunotherapy is among the most rapidly evolving treatment strategies in oncology. The therapeutic potential of immune-checkpoint...
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Journal of sports science & medicine 2018 05 1417(2) 259-268 Abstract The purpose of the study was to examine the effects of altering from habitual mixed Western-based (HD) to a very low-carbohydrate high-fat (VLCHF) diet...
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Journal of sports science & medicine 2018 05 1417(2) 167-173 Abstract The effects of concurrent strength and endurance training have been well studied in untrained and moderately-trained individuals. However, studies...
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Viruses 2010 02 052(2) 574-600 doi 10.3390/v2020574 Abstract The C-C chemokine receptor type 5 (CCR5) is a key player in HIV infection due to its major involvement in the infection process. Investigations into the role of the...
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Current biology : CB 2013 10 3123(22) 2255-61 doi 10.1016/j.cub.2013.09.019 Abstract Polo-like kinase 4 (Plk4) is a conserved master regulator of centriole assembly. Previously, we found that Drosophila Plk4 protein levels are...
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Journal of cell science 121(11) 1771 doi 10.1242/jcs.033340 Abstract
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Current biology : CB 2013 10 3123(22) 2245-54 doi 10.1016/j.cub.2013.09.037 Abstract Polo-like kinase 4 (PLK4) is a major player in centriole biogenesis: in its absence centrioles fail to form, while in excess leads to centriole...
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Nature communications 2018 05 159(1) 1911 doi 10.1038/s41467-018-04252-2 Abstract CRISPR is becoming an indispensable tool in biological research. Once known as the bacterial immune system against invading viruses, the...
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Scientific reports 2018 05 148(1) 7526 doi 10.1038/s41598-018-25919-2 Abstract Coffee’s long-term effect on cognitive function remains unclear with studies suggesting both benefits and adverse effects. We used Mendelian...
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Frontiers in physiology 2018 04 269() 403 doi 10.3389/fphys.2018.00403 Abstract The aim of the present work was to perform a meta-analysis evaluating the impact of recovery techniques on delayed onset muscle soreness (DOMS),...
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