Onset and duration of action and ease of use were classified higher as important parameters to...
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atient preference data for maintenance inhaler attributes can be used to identify a preference...
Read MoreIn an interim analysis of the first immunotherapy combination phase 1b trial with trastuzumab deruxtecan, safety results showed nivolumab with trastuzumab deruxtecan was well tolerated in patients with HER2-positive or HER2-low...
Read MoreIn an updated analysis of the phase 2 DESTINY-Breast01 study, women with HER2-positive metastatic breast cancer taking antibody-drug conjugate trastuzumab deruxtecan continued to demonstrate favorable efficacy data, durable...
Read MoreParticipants without cardiovascular disease but who were at increased risk were randomly assigned to receive a polypill (i.e. 1 statin with 3 blood pressure-lowering drugs) or placebo and to receive aspirin or placebo. With 4.6...
Read MorePhysician’s Weekly spoke with first author Nicholas A. Marston, MD, an Associate Physician in the Cardiovascular Division at Brigham and Women’s Hospital (Boston, USA), an Instructor of Medicine at Harvard Medical School, and an...
Read MoreHBM9036 ophthalmic solution 0.25%, also known as tanfanercept, a novel TNF-α inhibitor, is safe and effective for improving certain symptoms of dry eye disease, according to results of a phase 2 randomized, a double-blind...
Read MoreDry eye disease (DED) is a highly prevalent syndrome that manifests with symptoms that include constant irritation, burning or stinging sensations, and feelings of grittiness in the eyes. “DED is a chronic pain syndrome often...
Read MorePrevious research has shown that patients undergoing hematopoietic stem cell transplantation (HSCT) for hematologic malignancies, such as leukemia and lymphoma, are at a high risk of developing graft-versus-host disease (GVHD)....
Read MoreDry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability. The disease can significantly decrease quality of life as it impacts an...
Read MoreAccording to published research, as many as 77% of patients with cataracts present with common signs of dry eye disease (DED) prior to surgery. These signs include corneal staining, short tear breakup time, and hyperosmolarity,...
Read MoreWide-scale implementation of telemedicine has become increasingly important in a variety of medical fields, including ophthalmology, as the COVID-19 pandemic continues to impact healthcare delivery. It is well known that...
Read MoreContrast sensitivity is a key metric of visual function that strongly correlates with visual impairment and daily functional vision. Patients with age-related macular degeneration (AMD) often complain of visual dysfunction in...
Read MoreAge-related macular degeneration (AMD) continues to be the leading cause of blindness for people aged 60 years and older. For decades, cataract surgery has been controversial in the management of patients with AMD because it...
Read MoreAnti-vascular endothelial growth factor (VEGF) therapies have been revolutionary for the treatment of wet age-related macular degeneration (AMD), but unmet needs persist. Despite robust responses and visual gains in many...
Read MoreRecently approved by the European Medicines Association, and currently under review by the US Food and Drug Administration, inclisiran, a first-in-class small interfering RNA (siRNA) treatment, impressively improved primary...
Read MoreThe autotaxin inhibitor ziritaxestat proved to be efficacious and tolerable in the first randomised, double-blind, placebo-controlled phase 2 trial ever conducted in patients with diffuse cutaneous systemic sclerosis....
Read MoreThe anti-GM-CSF receptor alpha monoclonal antibody mavrilimumab entailed a lower risk of flare and greater sustained remission compared with placebo in patients with giant cell arteritis. A phase 2, randomised,...
Read MoreIn patients with osteoarthritis, a new study found that the vitamin K antagonist warfarin medication was associated with a significantly increased risk of joint replacement compared with treatment with direct oral...
Read MoreAn analysis of 681 patients with rheumatoid arthritis and systemic lupus erythematosus revealed that hydroxychloroquine use is not associated with QTc length prolongation, even when given in combination with other QTc-prolonging...
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