Genotypic Distribution and Disease Progression in ABCA4-Associated Retinal Disease
Severity and onset vary in ABCA4-associated retinal disease, with clinical presentation more predictive than genotype, suggests a study.
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Author: Devyn Osborne
Secondary Primary Malignancies Rare After CAR T-Cell Immunotherapy
Projected five-year incidence of 15.2 and 2.3% for solid and hematologic malignancies after CAR T-cell immunotherapy.
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Imetelstat Leads to Durable Red Blood Cell Transfusion Independence
For patients needing multiple infusions who are not responding to ESAs, imetelstat leads to durable red blood cell transfusion independence.
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Model for Early Prediction of Sepsis Improves Outcomes
COMPOSER deep learning model reduces in-hospital sepsis mortality by 1.9%, boosts bundle compliance by 5%, and lowers organ failure score change by 4%.
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Complications Lower With S. aureus Bacteremia in People Who Inject Drugs
In community-acquired Staphylococcus aureus bacteremia, people who inject drugs show lower mortality and reduced readmission odds without infective endocarditis.
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Lab-Driven Protocol Boosts PrEP Offerings for Women With STIs
A protocol using lab results was connected women with positive bacterial STIs to HIV PrEP at an urban hospital.
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Factors Influencing PrEP Uptake Among Black MSM, Transgender Women
PrEP remains underused among racial minorities due to various barriers, including low awareness, stigma, and medical mistrust.
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Identifying the Link Between SDoH & Multimorbidity in HIV
Comprehensive health and social care interventions for individuals with HIV is a necessity.
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HIV Incidence & Racial Inequities Among MSM
There is a need for targeted interventions to mitigate racial inequities in HIV transmission.
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Heightened Mortality Risk in Patients with Functional Seizures
Patients with functional seizures face increased mortality risk after treatment referral, with an SMR of 2.4, though deaths are unrelated to seizures.
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Validation of Machine Learning Models for Early Identification of Epilepsy Surgery Candidates
Machine learning identifies early candidates for epilepsy surgery, potentially shortening time to intervention.
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Decrease in Head and Neck Cancer Incidence Seen During Pandemic
During the first COVID-19 year, head and neck cancer incidence decreased, particularly in localized cases, suggesting pandemic impacts on diagnosis and care.
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Many With Meniere Disease Do Not Meet AAO-HNS Criteria
Many ICD-10-diagnosed Meniere disease patients do not meet AAO-HNS criteria, with 480 of 806 diagnoses aligning, revealing clinicodemographic variations.
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Self-Estimation of Weight Accurate in Emergency Care
Patient self-estimation of weight appears to be accurate in adult emergency care.
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Alternate Approaches Needed to ID Nonemergent Encounters
Only a small percentage of reasons for visits could be accurately categorized to a specific medical urgency category in a study.
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In Older Patients With IBD, Vaccine Reduces Shingles Risk
RZV reduces herpes zoster risk in IBD patients 50 or older, showing significant protection across age groups and both ulcerative colitis and Crohn’s disease.
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Optimizing Fecal Calprotectin Cutoffs for Assessing UC Endoscopic Activity
FC at 60 mcg/g effectively distinguishes Mayo endoscopic subscores in ulcerative colitis, aiding clinical remission prediction with high accuracy.
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Meningeal Artery Embolization Lowers Subdural Hematoma Risk
MMA embolization, coupled with surgery, reduces re-operation risk by nearly threefold for subacute or chronic SDH, minimizing subsequent SDH and drainage needs.
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BMI Ups Mortality in Patients With Severe Burns
Study results indicate that among patients with severe burns abnormal BMI appears to increase mortality rate.
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Hydrogel Burn Dressing Superior to Silver Sulfadiazine for Severe Burns
Hydrogel burn dressing had a superior effect on post-burn pain compared with silver sulfadiazine, according to a study.
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