32 Percent of U.S. Adults Know Someone Who Died of a Drug Overdose
MONDAY, June 3, 2024 (HealthDay News) — Thirty-two percent of U.S. adults report knowing...
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Personalized therapy does not reduce hospitalization in chronic kidney disease
1. In this randomized controlled trial, algorithmic identification based on electronic health...
Read MoreEarly specialised treatment for bipolar disorder: Long-term follow-up from the early intervention in affective disorders (EIA) randomised controlled trial.
It is unclear whether treatment early after onset in bipolar disorder may improve the long-term illness course. The early intervention in affective disorders (EIA) randomised controlled trial found that 2-years treatment in a...
Read MoreSteroid therapy in acute exacerbation of fibrotic interstitial lung disease.
Evidence for the benefit of steroid therapy in acute exacerbations (AEs) of idiopathic pulmonary fibrosis (IPF) is limited; however, they remain a cornerstone of management in other fibrotic interstitial lung diseases. This...
Read MoreRecent progress of iron-based nanomaterials in gene delivery and tumor gene therapy.
Gene therapy aims to modify or manipulate gene expression and change the biological characteristics of living cells to achieve the purpose of treating diseases. The safe, efficient, and stable expression of exogenous genes in...
Read MoreDevelopment of Ac-doped biocompatible nanoparticles for targeted alpha therapy.
Targeted alpha therapy (TAT) relies on chemical affinity or active targeting using radioimmunoconjugates as strategies to deliver α-emitting radionuclides to cancerous tissue. These strategies can be affected by transmetalation...
Read MoreThe perceptions of nurses and physicians in primary care of rehabilitation for frail older adults.
To investigate the perceptions of primary care nurses and physicians of the potential contributions of physiotherapists (PTs) and occupational therapists (OTs) in the treatment of frail older persons, as well as the obstacles...
Read MorePeritoneal dialysis-associated peritonitis, caused by superior mesenteric artery thrombosis with intestinal necrosis: a case report.
Peritoneal dialysis (PD)-associated peritonitis is a common complication of PD. Enteric peritonitis is defined as peritonitis arising from an intestinal or intra-abdominal organ source. The delay in the diagnosis or treatment of...
Read MoreZika Virus Infection Knowledge and Communication Preferences Among Women of Reproductive Age in Central Brooklyn, New York: A Thematic Analysis.
The 2016 outbreak of Zika virus (ZIKV) infected millions and resulted in thousands of infants born with malformations. Though the clusters of severe birth defects resulting from this outbreak have subsided, ZIKV continues to be...
Read MoreDereplication of 4-Quinolone Alkaloids from Waltheria indica (Malvaceae) Tissues Using Molecular Network Tools.
Waltheria indica (Malvaceae) is a plant popularly used in folk medicine by traditional African and indigenous communities, and in various countries worldwide, to treat general inflammation. Several biological activities of this...
Read MoreImaging of pancreatic serous cystadenoma and common imitators.
Pancreatic cystic neoplasms are lesions comprised of cystic components that show different biological behaviors, epidemiology, clinical manifestations, imaging features, and malignant potential and management. Benign cystic...
Read MoreGuillain-Barré Syndrome in a Patient Receiving Anti-Tumor Necrosis Factor for Crohn Disease: Coincidence or Consequence?
BACKGROUND Antibodies against tumor necrosis factor alpha (anti-TNF-alpha) are currently widely used in the treatment of inflammatory bowel diseases (IBD), despite a number of reported adverse effects. Diverse neurologic...
Read MoreGastroesophageal reflux disease and non-alcoholic fatty liver disease: a two-sample Mendelian randomization combined with meta-analysis.
Accumulating evidence from observational studies have suggested an association between gastroesophageal reflux disease (GERD) and non-alcoholic fatty liver disease (NAFLD). However, due to that such studies are prone to biases,...
Read MoreLong-Term Efficacy of Teprotumumab in Thyroid Eye Disease: Follow-Up Outcomes in Three Clinical Trials.
Thyroid eye disease (TED) is an autoimmune process characterized by extraocular muscle and orbital fat remodeling/expansion resulting in swelling, pain, redness, proptosis, and diplopia. Teprotumumab, an insulin-like growth...
Read MoreConstructing and validating a predictive nomogram for osteoporosis risk among Chinese single-center male population using the systemic immune-inflammation index.
Osteoporosis (OP) is a bone metabolism disease that is associated with inflammatory pathological mechanism. Nonetheless, rare studies have investigated the diagnostic effectiveness of immune-inflammation index in the male...
Read MoreProteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis.
Avascular necrosis (AVN) is a medical condition characterized by the destruction of bone tissue due to a diminished blood supply. When the rate of tissue destruction surpasses the rate of regeneration, effective treatment...
Read MorePsoriasis knowledge gaps and misconceptions in the Middle East and North Africa (MENA) regions: patients’ survey-based study.
Misconceptions among psoriatic patients often lead to a negative impact on disease outcomes.Our main target was knowledge assessment among a sample of psoriatic patients in the Middle East and North Africa (MENA) region where...
Read MorePrediabetes and diabetes were attributed to the prevalence and severity of sarcopenia in middle-aged and elderly adults.
Sarcopenia and diabetes are both prevalent health problems worldwide. However, little is known about the relationship between prediabetes and the prevalence and severity of sarcopenia. Therefore, the current study aimed to...
Read MoreEnzyme-Linked Immunosorbent Assay Accurately Measures Regenerating Island-Derived Protein 3E in Canine Blood
Regenerating island-derived proteins (REG) are upregulated in people with sepsis, pancreatitis, and gastrointestinal diseases. One member of the REG family, namely REG3E, was recently identified in pancreatic tissue and plasma...
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RASSF2 Gene Methylation Rate Higher in Patients With Prostate Cancer
Considering the inadequacy of prostate-specific antigen (PSA) measurement in the diagnosis of...
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