Adverse Social Determinants of Health Linked to Higher Prevalence of Prediabetes in Adolescents
Adverse social determinants of health (SDOH) are associated with higher prevalence of prediabetes...
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Hormone-modulating therapy decreased risk of dementia in breast cancer patients
1. In a retrospective cohort study of women newly diagnosed with breast cancer, use of hormone...
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Aerobic Exercise Tied to Improved Clinical Asthma Outcomes
MONDAY, June 24, 2024 (HealthDay News) — Moderate- and vigorous-intensity aerobic exercise...
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Atopic Dermatitis Negatively Impacts Mental Health
TUESDAY, April 23, 2024 (HealthDay News) — Atopic dermatitis (AD) negatively impacts...
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Tobacco Smoking Reduces the Odds of Psoriasis Improvement
WEDNESDAY, April 24, 2024 (HealthDay News) — Tobacco smoking is negatively associated with...
Read MoreTransforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability.
Dorsal root ganglion pulsed radiofrequency (DRG-PRF) is frequently used for the treatment of chronic lumbar radicular pain with good outcomes in terms of pain management. Transforaminal epidural steroid injection (TFESI) is...
Read MoreUsing item response theory to identify key symptoms of insomnia in a sample of university students with probable eating disorders.
Researchers have theorized that interactions between appetitive and circadian disruptions result in increased eating disorder (ED) symptoms and insomnia. However, it is unclear how specific insomnia symptoms present among people...
Read MoreBlood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care.
An accurate blood test for Alzheimer disease (AD) could streamline the diagnostic workup and treatment of AD.To prospectively evaluate a clinically available AD blood test in primary care and secondary care using predefined...
Read MoreInflammatory Bowel Disease as a Risk Factor for Complications and Revisions Following Lumbar Discectomy.
Retrospective cohort study.Patients with IBD are at an increased risk for postoperative complications following surgery. The goal of this study is to investigate if inflammatory bowel disease (IBD) is a risk factor for...
Read MoreEvaluation of β2-microglobulin in the condition and prognosis of psoriasis patients.
Numerous studies have linked the inflammatory pathway in psoriasis and metabolic disease, while no specific marker defined it. It is worth exploring the association of β2-microglobulin (β2M) in psoriasis severity and...
Read MoreClinical ocular surface characteristics and expression of MUC5AC in diabetics: a population-based study.
To investigate the clinical characteristics and the expression of mucin 5AC (MUC5AC) in in diabetic and non-diabetic subjects with or without dry eye disease.A total of 399 participants (796 eyes) aged 50-80 years were enrolled...
Read MoreLow-grade oncocytic tumor of the kidney: imaging features of a novel tumor entity.
Low-grade oncocytic tumor (LOT) is a rare renal tumor that has emerged from the spectrum of eosinophilic/oncocytic renal tumors and poses a diagnostic challenge due to its similarity to chromophobe renal cell carcinoma (CHRCC)...
Read MoreDiagnostic accuracy of ESR1 mutation detection by cell-free DNA in breast cancer: a systematic review and meta-analysis of diagnostic test accuracy.
Estrogen receptors express in nearly 70% of breast cancers (ER-positive). Estrogen receptor alpha plays a fundamental role as a significant factor in breast cancer progression for the early selection of therapeutic approaches....
Read MoreEZH2-STAT3 signaling pathway regulates GSDMD-mediated pyroptosis in glioblastoma.
Glioblastoma multiforme (GBM) is the most therapeutically challenging primary brain tumor owing to the unique physiological structure of the blood-brain barrier. Lately, research on targeted therapy for gliomas has shifted focus...
Read MoreFrom chromosomal aberrations to mutations in individual genes – the significance of genetic studies of chorions after miscarriage in the search for causes of miscarriages.
To determine the frequency of chromosomal aberrations in chorions after a miscarriage. The second was to examine selected euploid chorions using a next-generation sequencing (NGS) panel designed to assess 43 genes associated...
Read MoreUsing umbilical cord tissue to identify prenatal ethanol exposure and co-exposure to other commonly misused substances.
Substance misuse during pregnancy can result in a variety of poor pregnancy outcomes. Objective data reporting the prevalence of neonates born with ethanol metabolites (evidence of prenatal ethanol exposure) in their fluids or...
Read MoreHuman tripartite cortical network model for temporal assessment of alpha-synuclein aggregation and propagation in Parkinson’s Disease.
Previous studies have shown that aggregated alpha-synuclein (α-s) protein, a key pathological marker of Parkinson’s disease (PD), can propagate between cells, thus participating in disease progression. This prion-like...
Read MoreNaringenin ameliorates amyloid-β pathology and neuroinflammation in Alzheimer’s disease.
Alzheimer’s disease (AD) is the most common cause of dementia characterized by amyloid-β (Aβ) deposition, tau hyperphosphorylation, and neuroinflammation. Naringenin (NRG), a natural flavonoid widely present in citrus...
Read MoreDeveloping a phenotype risk score for tic disorders in a large, clinical biobank.
Tics are a common feature of early-onset neurodevelopmental disorders, characterized by involuntary and repetitive movements or sounds. Despite affecting up to 2% of children and having a genetic contribution, the underlying...
Read MoreIntrathecal baclofen therapy for spasticity in a person with spinal cord injury and end-stage renal disease dependent on hemodialysis: a case report.
Spasticity is one of the most common secondary complications following a spinal cord injury (SCI), which can significantly debilitate a patient irrespective of the severity of the injury. Intrathecal baclofen therapy can...
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