Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
Epigenetic changes are increasingly being appreciated as key events in breast cancer progression....
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Synthetic tumor-specific antigenic peptides with a strong affinity to HLA-A2 elicit anti-breast cancer immune response through activating CD8 T cells.
Researches on tumor-associated antigen have become a hot target in immunotherapy, but it stagnated...
Read More[Developments in mental health care in Dutch general practices: an overview of recent studies].
Dutch policy aims to strengthen mental health care in general practices, to keep health care affordable. Recently, a new function (mental health nurses) and a new referral model for patients with mental health problems were...
Read MoreThe dose of physical activity to minimise functional decline in older general medical patients receiving 24-hr acute care: A systematic scoping review.
To identify evidence for a recommended and feasible activity dose to minimise functional decline in older hospitalised general medical patients.Quality 24-hr care of older patients involves balancing activity to minimise...
Read MoreCare for people with psychiatric comorbidity in a general emergency unit: vision of the nurses.
To analyze the difficulties encountered by nurses when providing care to people with psychiatric comorbidity in the general emergency unit and their suggestions for improving the care of these patients.This is a qualitative,...
Read MorePolybrominated diphenyl ethers and novel brominated flame retardants in human milk from the general population in Beijing, China: Occurrence, temporal trends, nursing infants’ exposure and risk assessment.
The levels of eight polybrominated diphenyl ether (PBDE) congeners, and six novel brominated flame retardants (NBFRs) were determined in human milk collected from Beijing, China in 2014. The tested 111 samples were collected...
Read MoreCreating digitally ready nurses in general practice.
Digital healthcare provision in England has been driven mainly by a ‘top-down’ approach and a focus on digital infrastructure rather than front-line delivery. This has laid the foundation, but digital care delivery...
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Prolonged dual antiplatelet therapy in patients with non-ST-segment elevation myocardial infarction: 2-year findings from EPICOR Asia.
Patients with non-ST-segment elevation myocardial infarction (NSTEMI) have a generally poor...
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Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.
Blood lipids are causally involved in the pathogenesis of atherosclerosis, but their role in...
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Obstructive Sleep Apnea Severity and the Risk of Occupational Injury: A Prospective Observational Cohort.
To determine whether patients with obstructive sleep apnea (OSA) are at increased risk of...
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Accuracy of WatchPAT for the Diagnosis of Obstructive Sleep Apnea in Patients with Chronic Obstructive Pulmonary Disease.
The co-existence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea...
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Clinical challenges of a co-secreting TSH/GH pituitary adenoma.
Co-secreting thyrotropin/growth hormone (GH) pituitary adenomas are rare; their clinical...
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Efficacy of Digital Cognitive Behavioral Therapy for the Treatment of Insomnia Symptoms Among Pregnant Women: A Randomized Clinical Trial.
Despite the prevalence and adverse consequences of prenatal insomnia, a paucity of research is...
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Assessment of Mandibular Movement Monitoring With Machine Learning Analysis for the Diagnosis of Obstructive Sleep Apnea.
Given the high prevalence of obstructive sleep apnea (OSA), there is a need for simpler and...
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Neurological complications of pediatric cancer.
Both the onset of various malignancies as well as the treatment of cancer can lead to neurologic...
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Relationship between Sedative Antihistamines and the Duration of Febrile Seizures.
Some studies have shown that sedative antihistamines prolong febrile seizure duration. Although...
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Levels of diagnostic certainty for nonepileptic attack disorder in the neuropsychiatry setting.
Nonepileptic attack disorder (NEAD) is a medical condition commonly seen in neuropsychiatry...
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A convolutional neural network based framework for classification of seizure types.
Epileptic seizures are caused by a disturbance in the electrical activity of the brain and...
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Parental Knowledge, Attitudes, and Behaviors Toward Their Epileptic Children at King Abdulaziz University Hospital: Cross-Sectional Study.
Epilepsy is a chronic disease characterized by periodic seizures that result from abnormal...
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Does retina play a role in Parkinson’s Disease?
Visual disorder is one of the non-motor symptoms found in Parkinson’s disease (PD). It can...
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