Perceptions on gender disparity in surgery and surgical leadership: A multicenter mixed methods study.
Our objective was to identify perceptions of the environment for women in surgery among 4 academic...
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Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients
Recent studies have revealed that in critically ill patients, lung microbiota are altered and...
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Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study.
Acute respiratory distress syndrome (ARDS) is a lung inflammatory process caused mainly by sepsis....
Read MoreShared liability to pain, common mental disorders, and long-term work disability differs among women and men.
Knowledge of factors involved in the associations between pain, common mental disorders and future work incapacity is still scarce. The aim of this study was to examine the overlap between genetic and environmental factors...
Read Morec-Jun/p38MAPK/ASIC3 pathways specifically activated by NGF through TrkA is crucial for mechanical allodynia development.
Mechanical allodynia is a cardinal sign of several inflammatory pain disorders where Nerve Growth Factor, a prototypic neurotrophin, plays a crucial role by binding to TrkA receptors. Here, we took the advantage of our generated...
Read MoreNeck Pain and Headache Following Whiplash Injury
Neck pain and headache are two of the most common complications of whiplash injury. Therefore, we performed a systematic literature search on PubMed and Embase for publications reporting on the prevalence of neck pain and...
Read MorePharmacological characterization of a rat Nav1.7 loss-of-function model with insensitivity to pain.
Sodium channel Nav1.7, encoded by the SCN9A gene, is a well validated target that plays a key role in controlling pain sensation. Loss-of-function mutations of Nav1.7 can cause a syndrome of profound congenital insensitivity to...
Read MoreBrain networks and endogenous pain inhibition are modulated by age and sex in healthy rats.
Endogenous pain inhibition is less efficient in chronic pain patients. Diffuse noxious inhibitory control (DNIC), a form of endogenous pain inhibition, is compromised in women and older people, making them more vulnerable to...
Read MoreEfficacy of Pazopanib in patients with metastatic uterine sarcoma: A multi-institutional study.
Uterine sarcoma accounts for 3-9% of uterine malignant tumors and has poor prognosis. Pazopanib is an oral multi-kinase inhibitor and the only tyrosine kinase inhibitor which has been approved for metastatic soft tissue sarcoma....
Read MoreEfficacy of endostar combined with transcatheter arterial chemoembolization and analysis of vascular endothelial factor and C-reactive protein levels in patients with advanced hepatocellular carcinoma under contrast enhanced ultrasound.
To evaluate the effect of transcatheter arterial chemoembolization (TACE) under the guidance of contrast-enhanced ultrasound (CEUS) in patients with advanced hepatocellular carcinoma (HCC).One hundred and sixty patients with HCC...
Read MoreImpact of different therapeutic regimens on survival of patients with nasopharyngeal carcinoma.
Nasopharyngeal carcinoma (NPC) demonstrates specific histo-genetic features that affect its biological behaviour. Our aim was to investigate the correlation between different therapeutic approaches and survival of patients with...
Read MoreClinicopathological features and treatment outcomes of metastatic or locally unresectable small bowel adenocarcinoma.
Small bowel adenocarcinoma (SBA) is an uncommon malignancy with poor prognosis and therefore difficult to study. The purpose of this study was to evaluate the characteristics, treatments and prognostic factors in patients with...
Read MoreClinical-morphological features of wilms’ tumour: analysis of literature data and a case from practice
Wilms’ tumour, or nephroblastoma, is a malignant tumour, originating from nephrogenic germ cells that copy histology of developing kidneys and often contain cells at different stages of their differentiation. The article...
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Education Research: A novel resident-driven neurology quality improvement curriculum.
To describe and assess the effectiveness of a neurology resident quality improvement curriculum...
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Expression and Prognostic Value of IFIT1 and IFITM3 in Head and Neck Squamous Cell Carcinoma.
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) and interferon-induced...
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Genetic Factors in Acute Myeloid Leukemia With Myelodysplasia-Related Changes.
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous category...
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Immunohistochemical Assessment of the Diagnostic Utility of PD-L1 (Clone SP142) for Methotrexate-Associated Lymphoproliferative Disorders With an Emphasis of Neoplastic PD-L1 (Clone SP142)-Positive Classic Hodgkin Lymphoma Type.
We describe results of programmed death ligand 1 (PD-L1) immunohistochemical assessment in...
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Artificial Intelligence for Skin Cancer Assessment
The use of artificial intelligence (AI) for skin cancer assessment has been an emerging topic in...
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Inpatient teledermatology: Diagnostic and therapeutic concordance among hospitalist, dermatologist, and teledermatologist using store-and-forward teledermatology.
Inpatient dermatology has been shown to improve patient outcomes at a reduced cost. Few hospitals...
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Prenatal, infantile, and childhood tobacco exposure and risk of pediatric psoriasis in the Danish National Birth Cohort offspring.
Tobacco smoking is implicated in psoriasis among adults.To determine whether prenatal, infantile,...
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