- Physician's Weekly

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

Jan 30, 2020

AMPK is a central regulator of metabolism and autophagy. Here we show how lysosomal damage...

Insulin glargine in critically ill patients: Once-daily versus twice-daily dosing.

Jan 30, 2020

Twice-daily (BID) dosing of insulin glargine has been used to treat hyperglycemia in clinical...

Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study.

Jan 30, 2020

Skin diseases can have high morbidity that can be costly to society and individuals. To date,...

Expanding the Differential of Cutaneous Epithelioid Tumors: A Case of Dedifferentiated Liposarcoma with Epithelioid Features Involving the Skin and Review of the Literature.

Jan 30, 2020

Liposarcomas are categorized into four distinct histopathological subtypes: atypical lipomatous...

LncRNA HOTAIR promotes the invasion and metastasis of oral squamous cell carcinoma through metastasis-associated gene 2.

Jan 30, 2020

Despite therapeutic advancements, there has been little improvement in the survival status of...

Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination.

Jan 30, 2020

Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are currently...

Assessing potential mechanisms of arsenic-induced skin lesions and cancers: Human and in vitro evidence.

Jan 30, 2020

Environmental exposure to arsenic is a major public health challenge worldwide. In detailing the...

Ex-situ hypothermic perfusion of non-human primate pancreas: A feasibility study.

Jan 30, 2020

Pancreatic static cold storage is the gold-standard method for pancreas preservation. Our main...

Initial Lung Transplantation Experience with Uncontrolled Donation after Cardiac Death in North America.

Jan 30, 2020

Uncontrolled donation after cardiac death (uDCD) has the potential to ameliorate the shortage of...

Type D personality in patients who underwent coronary stenting

Jan 30, 2020

To evaluate the type D personality relation with clinical and instrumental parameters in patients...

Rise in Low-Density Lipoprotein Cholesterol during Hospitalization is Related with Poor Outcome at Discharge in Patients with Acute Ischemic Stroke.

Jan 30, 2020

The statistical association between a short-term rise in low-density lipoprotein cholesterol...

BLOCKADE OF ENDOTHELIAL, BUT NOT EPITHELIAL, CELL EXPRESSION OF PD-L1 FOLLOWING SEVERE SHOCK ATTENUATES THE DEVELOPMENT OF INDIRECT ACUTE LUNG INJURY IN MICE.

Jan 30, 2020

This study sets out to establish the comparative contribution of PD-L1 expression by pulmonary...

Prolonged minimal enteral nutrition versus early feeding advancements in preterm infants with birth weight ≤1250 g: a prospective randomized trial.

Jan 30, 2020

To determine the effect of two different feeding strategies on time to achieve full enteral...

Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.

Jan 30, 2020

The resolution phase of acute inflammation is essential for tissue homeostasis, yet the underlying...

In vitro Evaluation of Linezolid and Doripenem Clearance with Different Hemofilters.

Jan 30, 2020

Renal replacement therapy (RRT) is widely used in the treatment of septic acute kidney injury....

Lower Respiratory Tract Delivery, Airway Clearance, and Preclinical Efficacy of Inhaled GM-CSF in a Post-influenza Pneumococcal Pneumonia Model.

Jan 30, 2020

Inhaled GM-CSF shows promise as a therapeutic to treat viral and bacterial pneumonia, but to date,...

Respiratory immune system and consequences due to particulate matter in air pollution

Jan 30, 2020

The respiratory system is commonly known for being responsible for gaseous exchange. However,...

Respiratory syncytial virus infection: why does disease severity vary among individuals?

Jan 30, 2020

: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract...

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.

Jan 30, 2020

The initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan,...

Clinical Risk Factors of Thromboembolic and Major Bleeding Events for Patients with Atrial Fibrillation Treated with Rivaroxaban in Japan.

Jan 30, 2020

It is important to understand the risk of thromboembolism and bleeding in patients with...

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