Overcoming Resistance to Platinum-Based Drugs in Ovarian Cancer by Salinomycin and Its Derivatives-An In Vitro Study.
Polyether ionophore salinomycin (SAL) and its semi-synthetic derivatives are recognized as very...
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Strong Evidences of the Ovarian Carcinoma Risk in Women after IVF Treatment
In-vitro fertilization (IVF) has been very popular since the birth of the first...
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Should MMMT still be treated with adjuvant taxane-based combination chemotherapy?
Malignant mixed Mullerian tumors of endometrial (MMMT-E) and ovarian (MMMT-O) origin are...
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Trabectedin (Yondelis®) as a Therapeutic Option in Gynecological Cancers: A Focus on its Mechanisms of Action, Clinical Activity, and Genomic Predictors of Drug Response.
The use of predictive biomarkers provides potential individualized cancer therapeutic options to...
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PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin.
Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers and linked...
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Pregnancy and Live Birth Rates Are Comparable in Young Infertile Women Presenting with Severe Endometriosis and Tubal Infertility.
The aim of this study is to evaluate the effect of severe endometriosis in younger patients...
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TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Sertoli cells are important for spermatogenesis not only by directly interacting with germ line...
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Sperm Mitochondrial DNA Copy Number Is Not a Predictor of Intracytoplasmic Sperm Injection (ICSI) Cycle Outcomes.
This study is to determine if sperm mitochondrial DNA copy number (mtDNA CN) is associated with...
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Lack of Fetal Insulin Resistance in Maternal Polycystic Ovary Syndrome.
Polycystic ovary syndrome (PCOS) affects 8-10% of women. NIH criteria for diagnosis include...
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In silico elucidation of plausible inhibitory potential of Withaferin A of Withania somnifera medicinal herb against breast cancer targeting estrogen receptor.
Estrogen receptors (ER) are members of the nuclear intracellular receptors family. ER once...
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Anthracycline-induced cardiotoxicity prevention with angiotensin-converting enzyme inhibitor ramipril in low-risk breast cancer women: results of a prospective randomized study.
Anthracycline-induced cardiotoxicity (AIC) remains the main long-term and irreversible side effect...
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Sequential delivery of synergistic drugs by silica nanocarriers for enhanced tumour treatment.
Herein hybrid silica nanoparticles have been engineered to direct the sequential delivery of...
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Design, Synthesis, and Biological Evaluation of 2-(2-Bromo-3-nitrophenyl)-5-phenyl-1,3,4-oxadiazole Derivatives as Possible Anti-Breast Cancer Agents.
Breast Cancer (BCa) is the most often diagnosed cancer among women who were in the late...
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An alternative to standard lumpectomy: a 5-year case series review of oncoplastic breast surgery outcomes in a Canadian setting
Oncoplastic surgery (OPS) is becoming the new standard of care for breast-conserving surgery...
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Effects of Hemodynamic Conditions and Valve Sizing on Leaflet Bending Stress in Self-Expanding Transcatheter Aortic Valve: An In-vitro Study.
Transcatheter aortic valve (TAV) replacement has become a viable alternative to surgery for high...
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Determining the cut-off score for the Modified Barthel Index and the Modified Rankin Scale for assessment of functional independence and residual disability after stroke.
Assessment of functional independence and residual disability is very important for measuring...
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Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement.
There are scant data on long-term clinical outcomes and bioprosthetic-valve function after...
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Fear Extinction Memory is Negatively Associated with REM Sleep in Insomnia Disorder.
Formation and maintenance of fear-extinction memories are disrupted in Post-Traumatic Stress...
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Narcolepsy Severity Scale: A reliable tool assessing symptom severity and consequences.
To define clinically relevant Narcolepsy Severity Scale (NSS) score ranges, confirm its main...
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Altered surface expression of P2Y receptor with narcolepsy-associated mutations.
Narcolepsy with cataplexy is a neurological sleep disorder, which is believed to arise from the...
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