- Physician's Weekly

Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease.

Apr 29, 2024

Inflammatory bowel disease (IBD) is one of the intractable diseases. Nutritional components...

Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3′-diaminobenzidine-stained esophageal biopsies.

Apr 29, 2024

Eosinophilic esophagitis (EoE) and gastroesophageal reflux disease (GERD) share many histopathological features; therefore, markers for differentiation are of diagnostic interest and may add to the understanding of the...

Association of serum sclerostin levels with marrow adiposity in postmenopausal women with glucocorticoid-induced osteoporosis.

Apr 29, 2024

Glucocorticoids and sclerostin act as inhibitors of the Wnt signaling pathway, thereby hindering bone formation. Given the pathway’s intricate association with mesenchymal stem cells, the hypothesis suggests that...

Association of stress hyperglycemia ratio and mortality in patients with sepsis: results from 13,199 patients.

Apr 29, 2024

The stress hyperglycemia ratio (SHR), adjusted for average glycemic status, is suggested for assessing actual blood glucose levels. Its link with adverse outcomes is known in certain populations, yet its impact on sepsis...

Short-term outcomes after liver resection with vascular reconstruction: Results from a study with the National Clinical Database of Japan.

Apr 29, 2024

Although curative resection with vascular reconstruction improves the prognosis of blood-invading locally advanced hepatobiliary tumors, the mortality and morbidity of the procedure remains unclear. This study aimed to clarify...

Short-term variation of the fetal heart rate as a marker of intraamniotic infection in pregnancies with preterm prelabor rupture of membranes: a historical cohort study.

Apr 29, 2024

Intraamniotic infection (IAI) and subsequent early-onset neonatal sepsis (EONS) are among the main complications associated with preterm prelabor rupture of membranes (PPROM). Currently used diagnostic tools have been shown to...

In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula.

Apr 29, 2024

The unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are...

A review on the nexus of autophagy genes from the perspective of polycystic ovary syndrome.

Apr 29, 2024

Polycystic ovary syndrome or PCOS is an endocrine disorder in women of reproductive age. It is a diversified multi factorial disorder and diagnosis is very complicated because of its overlapping symptoms some of which are...

Awareness of having hypertension, diabetes and dyslipidaemia among US adults: The 2011-2018 NHANES data.

Apr 29, 2024

This study aimed to investigate awareness of having hypertension, diabetes and dyslipidaemia and their associated factors among US adults.Data from the National Health and Nutrition Examination Survey, including 21,399 adults...

Predictive Value of Nasal Nitric Oxide for Diagnosing Eosinophilic Chronic Rhinosinusitis

Apr 29, 2024

The primary aim of this study was to assess disparities in nasal nitric oxide (NO) levels between...

Poor respiratory function is associated with greater incidence of depression

Apr 28, 2024

1. In a cohort of patients with varying lung function assessed through values of FVC and FEV1, and...

GLP1 Receptor Agonists Do Not Up Risk for Complications After Emergency Surgery

Apr 26, 2024

The risk for postoperative respiratory complications is similar among patients undergoing...

Genetics Studies Have a Diversity Problem That Researchers Struggle To Fix

Apr 26, 2024

CHARLESTON, S.C. — When he recently walked into the dental clinic at the Medical University of South Carolina donning a bright-blue pullover with “In Our DNA SC” embroidered prominently on the front, Lee Moultrie...

Mandatory Reporting Laws Meant To Protect Children Get Another Look

Apr 26, 2024

More than 60 years ago, policymakers in Colorado embraced the idea that early intervention could prevent child abuse and save lives. The state’s requirement that certain professionals tell officials when they suspect a...