No Association Found for Autoimmune Disease, Monoclonal Gammopathy
MONDAY, May 20, 2024 (HealthDay News) — In a systematically screened population, there is no...
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Long COVID Definitions, Care Models Are Evolving
MONDAY, May 20, 2024 (HealthDay News) — Definitions of long COVID and care models are...
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CDC Warns Muslim Pilgrims to Saudi Arabia of Meningitis Outbreak
WEDNESDAY, May 22, 2024 (HealthDay News) — Muslim pilgrims attending the annual Hajj could...
Read MorePeriodontal inflammatory and microbial profiles in healthy young African Americans and Caucasians.
This study aimed to compare microbial and inflammatory profiles in periodontally/systemically healthy African American (AA) and Caucasian (C) individuals.Thirty-seven C and 46 AA aged from 5 to 25 years were evaluated regarding...
Read MoreBisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial.
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Observational studies report that β-blocker use may be associated with reduced risk of COPD exacerbations. However, a recent...
Read MoreAssociation between maternal antidepressant use during pregnancy and the risk of autism spectrum disorder and attention deficit hyperactivity disorder in offspring.
Prenatal antidepressant exposure has been reported to be associated with adverse neurodevelopmental outcomes, yet studies considering confounding factors in Asian populations are lacking. This study utilized a nationwide data...
Read MoreAngiopoietin-like 4 is upregulated by amphiregulin and activates cell proliferation and migration through p38 kinase in head and neck squamous cell carcinoma.
Angiopoietin-like 4 is a molecular hallmark that correlates with the growth and metastasis of head and neck squamous cell carcinoma, one of the most prevalent cancers worldwide. However, the molecular mechanisms by which...
Read MoreThe impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients.
Glioblastoma (GBM) is an aggressive brain tumor in which primary therapy is standardized and consists of surgery, radiotherapy (RT), and chemotherapy. However, the optimal time from surgery to start of RT is unknown. A...
Read MoreRecent Insights into the Roles of PEST-Containing Nuclear Protein.
PEST-containing nuclear protein (PCNP), a short-lived small nuclear protein with 178 amino acids, is a nuclear protein containing two PEST sequences. PCNP is highly expressed in several malignant tumors such as cervical cancer,...
Read MoreAssessment of secular trends of three major gynecologic cancers burden and attributable risk factors from 1990 to 2019: an age period cohort analysis.
This study aims to assess the long-term trends in the burden of three major gynecologic cancers(GCs) stratified by social-demographic status across the world from 1990 to 2019. To assess the trends of risk factor attributed...
Read MoreExosomes regulate SIRT3-related autophagy by delivering miR-421 to regulate macrophage polarization and participate in OSA-related NAFLD.
To analyze the role of and mechanism underlying obstructive sleep apnea (OSA)-derived exosomes in inducing non-alcoholic fatty liver (NAFLD).The role of OSA-derived exosomes was analyzed in inducing hepatocyte fat accumulation...
Read MoreGenicular nerve radiofrequency ablation: a systematic review of application for perioperative pain control in total knee arthroplasty and as treatment for chronic pain in well-appearing total knee arthroplasty.
Total knee arthroplasty (TKA) is a successful treatment for end-stage osteoarthritis, yet some patients still experience postoperative pain. Genicular nerve radiofrequency ablation (GNRFA) has become a potential modality to...
Read MoreExploring molecular mechanisms, therapeutic strategies, and clinical manifestations of Huntington’s disease.
Huntington’s disease (HD) is a paradigm of a genetic neurodegenerative disorder characterized by the expansion of CAG repeats in the HTT gene. This extensive review investigates the molecular complexities of HD by...
Read MorePrevalence and risk factors for chronic kidney disease among older adult patients with schizophrenia in Taiwan.
There is an increasing incidence and prevalence of patients with chronic kidney disease (CKD) worldwide. Little is known the prevalence of CKD among older patients with schizophrenia. The purpose of this study was to investigate...
Read MoreInfluenza surveillance in pigs: balancing act between broad diagnostic coverage and specific virus characterization.
Monitoring of infectious diseases on swine farms requires a high diagnostic sensitivity and specificity of the test system. Moreover, particularly in cases of swine influenza A virus (swIAV) it is desirable to include...
Read MoreHomeostatic T helper 17 cell responses triggered by complex microbiota are maintained in ex vivo intestinal tissue slices.
Segmented filamentous bacteria (SFB) are members of the commensal intestinal microbiome. They are known to contribute to the postnatal maturation of the gut immune system, but also to augment inflammatory conditions in chronic...
Read MoreOsteocyte ferroptosis induced by ATF3/TFR1 contributes to cortical bone loss during ageing.
Cortical bone loss is intricately associated with ageing and coincides with iron accumulation. The precise role of ferroptosis, characterized by iron overload and lipid peroxidation, in senescent osteocytes remains elusive. We...
Read MoreConserved genes regulating human sex differentiation, gametogenesis and fertilization.
The study of the functional genome in mice and humans has been instrumental for describing the conserved molecular mechanisms regulating human reproductive biology, and for defining the etiologies of monogenic fertility...
Read MoreProbiotic-derived amphiphilic exopolysaccharide self-assembling adjuvant delivery platform for enhancing immune responses.
Enhancing immune response activation through the synergy of effective antigen delivery and immune enhancement using natural, biodegradable materials with immune-adjuvant capabilities is challenging. Here, we present NAPS that...
Read MoreTCL1A-expressing B cells are critical for tertiary lymphoid structure formation and the prognosis of oral squamous cell carcinoma.
Oral squamous cell carcinoma (OSCC) is a malignant tumor with a poor prognosis. Traditional treatments have limited effectiveness. Regulation of the immune response represents a promising new approach for OSCC treatment. B cells...
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