Lifestyle and socioeconomic status have been associated with health risks, morbidity, and mortality. However, the exact association is not well documented. This study aims to assess the lifestyle mediate associations of socioeconomic status (SES) with the risk of mortality and cardiovascular disease (CVD).

This population-based cohort study included a total of 44,462 US adults aged 20 or older and 399,537 UD adults aged 37-73 years. The SES of all participants was examined by latent class analysis using family income, employment status, health insurance, and education levels. lifestyle habits, including smoking and heavy alcohol consumption, were also considered. The primary outcome of the study was all-cause mortality, along with CVD mortality and morbidity.

Over the mean follow-up of 8-11 years, US NHANES reported 8,906 deaths, and UK Biobank documented 22,309 deaths and 6.903 incident CVD cases. The findings indicated that the age-adjusted risk of death was 22.5 per 1000 person-years among adults with low SES. Compared with adults with high SES, those with low SES were at a higher risk of all-cause mortality, CVD mortality, and incident CVD.

The research concluded that unhealthy lifestyles and low SES were associated with a higher risk of all-cause mortality, CVD mortality, and CVD incidence in adults.

Ref: https://www.bmj.com/content/373/bmj.n604

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