The health effect of particulate matter pollution on stroke has been widely examined; however, the effect among patients with comorbid type 2 diabetes (T2D) in developing countries has remained largely unknown.
A time-series study was conducted to investigate the short-term effect of fine particulate matter (PM) and inhalable particulate matter (PM) on hospital admissions for stroke among patients with T2D in Beijing, China, from 2014 to 2018. An over-dispersed Poisson generalized additive model was employed to adjust for important covariates, such as weather conditions and long-term and seasonal trends.
A total of 159,298 hospital admissions for stroke comorbid with T2D were reported. Approximately linear exposure-response curves were observed for PM and PM in relation to stroke admissions among T2D patients. A 10 μg/m increase in the four-day moving average of PM and PM was associated with 0.14% (95% confidence interval [CI]: 0.05-0.23%) and 0.14% (95% CI: 0.06-0.22%) incremental increases in stroke admissions among T2D patients, respectively. A 10 μg/m increase in PM in the two-day moving average corresponded to a 0.72% (95% CI: 0.02-1.42%) incremental increase in hemorrhagic stroke, and a 10 μg/m increase in PM in the four-day moving average corresponded to a 0.14% (95% CI: 0.06-0.22%) incremental increase in ischemic stroke.
High particulate matter might be a risk factor for stroke among patients with T2D. PM and PM have a linear exposure-response relationship with stroke among T2D patients. The study provided evidence of the risk of stroke due to particulate matter pollution among patients with comorbid T2D.
Copyright © 2021. Published by Elsevier Inc.
About The Expert
Xiangtong Liu
Zhiwei Li
Moning Guo
Jie Zhang
Lixin Tao
Xiaolin Xu
Aklilu Deginet
Feng Lu
Yanxia Luo
Mengmeng Liu
Mengyang Liu
Yue Sun
Haibin Li
Xiuhua Guo
References
PubMed