One of the primary reasons for complications and death worldwide are cardiovascular diseases (CVDs), with a death toll of approximately 18 million per year. CVDs includes cardiomyopathy, hypertension, ischemic heart disease, coronary heart disease, myocardial infarction, heart attack, hearth failure etc. Over 80% of the CVD mortality is recorded from lower and middle-income countries. Records from the past decade have highlighted the increase of CVDs among the South Asian populations, and the prime purpose of the review is to jot down the reasons for the steep spike in CVDs. Studies analyzing the causative factors for the increase of CVDs in South Asians are still to be verified. Apart from known predisposing and lifestyle factors, other emerging risk factors associated with CVDs, namely the musculoskeletal diseases sarcopenia and osteopenia, should be tracked to tackle research gaps in upcoming analyses. This requires loads of scientific efforts. With proper monitoring, the raising alarm that the CVD burden generates can be reduced. This review discusses the already established signs and recognizes important clues to the emerging etiology of CVDs in the Asian population and prevention measures to keep it at bay.Copyright © 2023. Published by Elsevier Inc.
REFERENCES & ADDITIONAL READING
Haripriya Kuchi Bhotla
Department of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India;. Electronic address: hpriya9121@gmail.com.
Arun Meyyazhagan
Department of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India;; Dipartimento di Medicina e Chirurgia, Università di Perugia, Perugia, Italy.. Electronic address: arun47biotech@gmail.com.
Karthika Pushparaj
Department of Zoology, School of Biosciences, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore – 641 043, Tamil Nadu, India;. Electronic address: karthika_zoo@avinuty.ac.in.
Manikantan Pappuswamy
Department of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India;. Electronic address: manikantan.p@christuniversity.in.
Aditi Chaudhary
Department of Life Science, CHRIST (Deemed to be University), Bengaluru, Karnataka 560076, India;. Electronic address: aditi.chaudhary@res.christuniversity.in.
Vijaya Anand Arumugam
Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore- 641 046, Tamil Nadu, India;. Electronic address: avahgmb@buc.edu.in.
Balamuralikrishnan Balasubramanian
Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, South Korea;. Electronic address: geneticsmurali@gmail.com.
Durairaj Ragu Varman
Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia-23220.. Electronic address: ragu.durairaj@vcuhealth.org.
Antonio Orlacchio
Dipartimento di Medicina e Chirurgia, Università di Perugia, Perugia, Italy.. Electronic address: antonio.orlacchio@unipg.it.
Kannan Rr Rengasamy
Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, India;. Electronic address: ragupathir.sdc@saveetha.com.
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