Patients with punctate inner choroidopathy (PIC) require proper eye care. They develop secondary complications like choroidal neovascularization (CNV). Clinicians have to monitor these disorders and provide efficient treatment. This study compares diagnostic techniques dye angiography and optical coherence tomography angiography(OCTA) to improve CNV in PIC assessments.
The study was conducted in China for over 3 1/2 years. A total of 123 consecutive patients with PIC were assessed. The study involved 160 affected eyes with comprehensive testing during the same visit. Clinicians performed multimodal imaging and comprehensive ophthalmological examinations. The diagnostic accuracy, sensitivity, and specificity were evaluated. This cross-sectional study also involved data collection, analysis, and design of experiments.
Multimodal imaging was used to identify secondary CNV in 95 eyes or 59.38%. OCTA’s sensitivity and specificity for CNV detection were 89.47% and 98.46%, respectively. It facilitated CNV activity determination by providing the morphology with sensitivity and specificity of 86.7% and 94.29%.
The study investigated OCTA’s usefulness in assessing CNV in PIC patients. It was diagnostically more accurate and convincing than dye angiography. But, OCTA has limited potential, and it cannot replace dye angiography in clinical set-ups. But it offers a non-invasive procedure to monitor the patients.
Ref: https://bjo.bmj.com/content/early/2020/12/23/bjophthalmol-2020-318191
