Neutrophils are one of the most plentiful cells of the insusceptible framework and they are amazingly dynamic during the maintenance of cutaneous injuries. When all is said in done, the antimicrobial action of neutrophils is compelling and permits these cells to complete their essential capacity of keeping wounds from getting tainted. It is currently realized that notwithstanding sanitizing the injury, the weapons utilized by neutrophils to slaughter potential microbes can likewise cause critical tissue harm to the host. This extra harm can prompt postponed mending and exorbitant scar development. A large part of the host harm brought about by neutrophils results from the movement of proteases discharged by these cells. The clinical noteworthiness of this issue is featured by various investigations indicating that significant levels of neutrophil-inferred proteases are related with ongoing, non-mending wounds. Studies are as of now being performed to assess better approaches for checking protease action in constant injuries. Extra investigations should be completed to decide if killing neutrophil proteases can improve the mending of ongoing injuries without giving up the capacity of neutrophils to dispose of microorganisms and gambling disease.
Reference link- https://www.liebertpub.com/doi/full/10.1089/wound.2012.0383
