This study was done to examine the correlation between IOP reduction and the number of hyper-reflective particles appearing in the anterior chamber following SLT.
It was a prospective interventional study. Open-angle glaucoma patients were included in the study. All participants received a standardized SLT session. Anterior segment optical coherence tomography and applanation tonometry were performed before SLT and 15 min, 1 day, 1 week, 1 month, and 3 months after. Particles were counted on cross-sectional scans using a standardized algorithm.
A total of 25 patients was included in the study with a baseline IOP of 21.4±4.5 mm Hg. IOP at month 1 and month 3 after SLT was 18.0±4.0 and 17.4±3.3 mm Hg, respectively. The mean number of anterior chamber particles before and 15 min after SLT were checked. There was a statistically significant correlation between the mean number of anterior chamber particles 15 min after SLT and IOP reduction at 1 month and 3 months.
The study concluded through its findings that the number of the anterior chamber particles graded using anterior segment optical coherence tomography after the procedure correlates with the IOP-lowering effect of SLT.
Reference: https://bjo.bmj.com/content/104/11/1508
