The study was done to devise a description of the multimodal imaging findings of retinal lesions that clinically resemble retinal astrocytic hamartomas (RAHs), but also have unique characteristics that we believe come under the category of a novel variant.
This study was done through the method of observational study to collect data and devise deductions. Five eyes in five patients (one eye per person) with solitary retinal lesions evaluated at the retina division of three institutions. The study provided the description for the multimodal imaging findings including fundus photography, fundus autofluorescence, fluorescein angiography, spectral-domain optical coherence tomography (OCT), swept-source OCT, swept-source OCT angiography and ultrasonography.
The retinal lesions described shared similar appearance to RAHs but demonstrated unique features such as glistening granular appearance on fundus photographs with perivascular hyperreflectivity with OCT and OCT angiography.The unique characteristics that we believe come under the category of a novel variant.
The study concluded that the lesions described herein appear to have unique characteristics that warrant a designation as a novel RAH variant. The name presumed retinal pericapillary astrocytic hamartoma is suggested.
Reference: https://bjo.bmj.com/content/early/2020/09/26/bjophthalmol-2020-317670
