Both total and non-total arterial revascularizations (AR) are used to improve short- and long-term mortality in patients with coronary artery bypass grafting (CABG). However, the long-term outcomes of total and non-total AR are not known. The objective of this study is to evaluate the long-term clinical outcomes of total and non-total AR.
This is a multicenter, population-based, cohort study conducted using a propensity score matching in Ontario, Canada. The study included a total of 49,404 patients with primary isolated CABG, 2,433 of whom received total AR, with the number of bypasses being 2, 3, and 4 in 1,521, 865, and 47 individuals, respectively. The primary outcome of the study was in-hospital deaths, cardiovascular events, and overall freedom from major cardiovascular disease.
In-hospital deaths for total AR and non-total AR groups did not differ significantly. At eight years of follow-up, total AR was linked with improved recovery from adverse cardiac events, cerebrovascular events, and myocardial infarctions. However, no significant difference was found in the risk of stroke and recurring revascularization.
The research concluded that total AR was associated with an improved long-term freedom from cardiac events, cerebrovascular events, and death. However, there was no substantial difference in the risk of stroke and recurring revascularization.
Ref: https://jamanetwork.com/journals/jamacardiology/article-abstract/2761528?resultClick=1
