To evaluate the impact of COVID-19 pandemic migitation measures on of ST-elevation myocardial infarction (STEMI) care.
We previously reported a 38% decline in cardiac catheterization activations during the early phase of the COVID-19 pandemic mitigation measures. This study extends our early observations using a larger sample of STEMI programs representative of different US regions with the inclusion of more contemporary data.
Data from 18 hospitals or healthcare systems in the US from January 2019 to April 2020 were collecting including number activations for STEMI, the number of activations leading to angiography and primary percutaneous coronary intervention (PPCI), and average door to balloon (D2B) times. Two periods, January 2019-February 2020 and March-April 2020, were defined to represent periods before (BC) and after (AC) initiation of pandemic mitigation measures, respectively. A generalized estimating equations approach was used to estimate the change in response variables at AC from BC.
Compared to BC, the AC period was characterized by a marked reduction in the number of activations for STEMI (29%, 95% CI:18-38, p < .001), number of activations leading to angiography (34%, 95% CI: 12-50, p = .005) and number of activations leading to PPCI (20%, 95% CI: 11-27, p < .001). A decline in STEMI activations drove the reductions in angiography and PPCI volumes. Relative to BC, the D2B times in the AC period increased on average by 20%, 95%CI (-0.2 to 44, p = .05).
The COVID-19 Pandemic has adversely affected many aspects of STEMI care, including timely access to the cardiac catheterization laboratory for PPCI.
© 2020 Wiley Periodicals LLC.
About The Expert
Santiago Garcia
Larissa Stanberry
Christian Schmidt
Scott Sharkey
Michael Megaly
Mazen S Albaghdadi
Perwaiz M Meraj
Ross Garberich
Farouc A Jaffer
Ada C Stefanescu Schmidt
Simon R Dixon
Jeffrey J Rade
Timothy Smith
Mark Tannenbaum
Jenny Chambers
Frank Aguirre
Paul P Huang
Dharam J Kumbhani
Thomas Koshy
Dmitriy N Feldman
Jay Giri
Prashant Kaul
Craig Thompson
Houman Khalili
Brij Maini
Keshav R Nayak
Mauricio G Cohen
Sripal Bangalore
Binita Shah
Timothy D Henry
References
PubMed