The following is the summary of “Endometrial microstimulation effects on endometrial receptivity assessed by transvaginal color Doppler sonography” published in the December 2022 issue of Women’s health by Cheng, et al.
The purpose of this study was to use transvaginal color Doppler sonography (TVCDS) to assess the impact of endometrial microstimulation (EM) on endometrial receptivity. About 30 women in the EM group (women of reproductive age trying to conceive) were evaluated by EM between days 3 and 5 of their menstrual cycle, while the remaining 60 women served as a control group. During the implantation window, TVCDS was performed to measure endometrial thickness, endometrial pattern, endometrial mobility, blood flow type, and uterine and spiral arterial hemodynamic parameters. To establish distinctions between the groups, a comparison was made.
Endometrial thickness (0.97 ± 0.18 cm and 0.95 ± 0.17 cm), endometrial movement (type 1: 46.7% and 51.7%; type 2: 30.0% and 28.3%; type 3: 6.7% and 5.0%; type 5: 16.7% and 15.0%), and hemodynamic parameters of the uterine (pulsatility index [PI]: 2.46 ± 0.50 and 2.41 ± 0.48; resistance index [RI]: 0.85 ± 0.05 and 0.84 ± 0.05) and spiral (PI: 1.11 ± 0.32 and 1.19 ± 0.33; RI: 0.48 ± 0.11 and 0.51 ± 0.08) arteries did not differ significantly between groups (P>0.05).
However, the endometrial pattern (a trilaminar pattern: 80.0% and 58.3%; P=0.041) and blood flow type (type I: 16.7% and 43.3%; type II: 63.3% and 40.0%; type III 20.0% and 16.7%; P=0.038) differed significantly between groups. Microstimulation of the endometrium did not influence uterine or spiral arterial blood flow characteristics or endometrial pathological staging, thickness, or morphology. But it could be able to sand down aberrant endometrial tissue, making for a more desirable endometrial pattern. Endometrial microstimulation has the potential to promote local spiral artery regeneration and boost endometrial blood flow at the start of subsequent menstrual cycles.
Source:
bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-022-02096-z
