Mar 25, 2024
Suxamethonium is hydrolysed by butyrylcholinesterase (BChE) and a low BChE activity can result in a prolonged duration of action of suxamethonium. The BChE activity is reduced during pregnancy and postpartum period by up to 33%....
Read MoreMar 25, 2024
Chronic postsurgical pain (CPSP) presents a considerable healthcare challenge, impacting patients, and healthcare providers, particularly in the context of gastrointestinal surgery. The notable incidence of CPSP in this specific...
Read MoreMar 25, 2024
Botulinum toxin, produced by the Gram-positive anaerobe Clostridium botulinum, is composed of seven antigenic subtypes (A, B, C, D, E, F, and G). Currently, only Botulinum toxin type A, commonly referred to as...
Read MoreMar 25, 2024
Hyperphosphorylation and aggregation of the protein tau play key roles in the development of Alzheimer’s disease (AD). While the molecular structure of the filamentous tau aggregates has been determined to atomic...
Read MoreMar 25, 2024
Rheumatoid arthritis is a chronic autoimmune inflammatory disease characterized by immune response overexpression, causing pain and swelling in the synovial joints. This condition is caused by auto-reactive antibodies that...
Read MoreMar 25, 2024
Women face a significant change in their reproductive health as menopause sets in. It is marred with numerous physiological changes that negatively impact their quality of life. This universal, transition phase is associated...
Read MoreMar 25, 2024
This study aimed to investigate the responses of periodontal environment to hormone replacement therapy (HRT) in postmenopausal women with or without periodontitis.HRT is a common and effective strategy for controlling...
Read MoreMar 25, 2024
Dysregulation of the host immune response has a central role in the pathophysiology of sepsis. There has been much interest in immunomodulatory drugs as potential therapeutic adjuncts in sepsis. We conducted a systematic review...
Read MoreMar 25, 2024
Venous thromboembolism (VTE) is a leading cause of preventable in-hospital mortality. Monitoring VTE cases is limited by the challenges of manual chart review and diagnosis code interpretation. Natural language processing (NLP)...
Read MoreMar 18, 2024
Erectile dysfunction (ED) is a common condition that affects millions worldwide. Patients and urologists alike are seeking alternative therapies that can provide long-lasting results in the treatment of ED. This review provides...
Read MoreMar 18, 2024
The Learning Ratio (LR) is a novel learning score that has shown improved utility over other learning metrics in detecting Alzheimer’s disease (AD) across multiple memory tasks. However, its utility on the Consortium to...
Read MoreMar 18, 2024
The study presented here aimed to establish a predictive model for heart failure (HF) and all-cause mortality in peritoneal dialysis (PD) patients with machine learning (ML) algorithm.We retrospectively included 1006 patients...
Read MoreMar 18, 2024
Dolutegravir + lamivudine (DTG + 3TC) is a first-line regimen for people with HIV. However, there are still concerns about its efficacy in people with tuberculosis (TB)/HIV due to the lack of available evidence and drug-drug...
Read MoreMar 18, 2024
The debate continues as to whether laparoscopic total Nissen (LNF) versus partial posterior Toupet fundoplication (LTF) leads to better outcomes in the surgical treatment of axial hiatal hernia with gastroesophageal reflux...
Read MoreMar 18, 2024
Poorer sleep is associated with poorer bone health among older adults but the role of sleep in bone health during younger adulthood is understudied. In this observational study, the averages and variability in total sleep time...
Read MoreMar 18, 2024
The present study aimed to examine the impact of lifetime blast exposure (LBE) on neuropsychological functioning in service members and veterans (SMVs). Participants were 282 SMVs, with and without history of traumatic brain...
Read MoreMar 18, 2024
This case study reports on a suicide attempt involving indoxacarb and vitamin C. Indoxacarb is a neurotoxic insecticide used in agriculture and as a flea controller in pets. Cotton, vegetables, and fruits are treated with...
Read MoreMar 18, 2024
Vomocytosis, also known as nonlytic exocytosis, is a process whereby fully phagocytosed microbes are expelled from phagocytes without discernible damage to either the phagocyte or microbe. Although this phenomenon was first...
Read MoreMar 11, 2024
Penile induration disease, commonly known as Peyronie’s disease (PD), is a connective tissue disorder that affects the penis, leading to the development of fibrous plaques, penile curvature, and erectile dysfunction. PD is...
Read MoreMar 11, 2024
Spinal pain syndromes have a severe impact on the patient’s sex life, contributing to a decrease in sexual function and sexual satisfaction. Despite the importance of sexual health on mental and physical wellbeing, sexual...
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